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公开(公告)号：EP2276756B8
公开(公告)日：2012-04-11
申请号：EP09726601.9
申请日：2009-04-02
Applicant: Merck Sharp & Dohme Corp.
Inventor： BERGER, Richard , CHANG, Lehua , EDMONDSON, Scott, D. , GOBLE, Stephen, D. , HA, Sookhee, Nicole , KAR, Nam, Fung , KOPKA, Ihor, E. , LI, Bing , MORRIELLO, Gregori, J. , MOYES, Chris, R. , SHEN, Dong-Ming , WANG, Liping , ZHU, Cheng
IPC: C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04 , C07D487/04 , A61P13/00 , A61K31/4178 , A61K31/506
CPC classification number: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
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Patent Agency Ranking
公开(公告)号：EP2276756A1
公开(公告)日：2011-01-26
申请号：EP09726601.9
申请日：2009-04-02
Applicant: Merck Sharp & Dohme Corp.
Inventor： BERGER, Richard , CHANG, Lehua , EDMONDSON, Scott, D. , GOBLE, Stephen, D. , HA, Sookhee, Nicole , KAR, Nam, Fung , KOPKA, Ihor, E. , LI, Bing , MORRIELLO, Gregori, J. , MOYES, Chris, R. , SHEN, Dong-Ming , WANG, Liping , ZHU, Cheng
IPC: C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04 , C07D487/04 , A61P13/00 , A61K31/4178 , A61K31/506
CPC classification number: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
Abstract translation: 本发明提供式（I）的化合物，其药物组合物及其在治疗或预防由β3-肾上腺素受体激活介导的疾病中的使用方法。
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公开(公告)号：EP2274296B1
公开(公告)日：2012-10-17
申请号：EP09726940.1
申请日：2009-03-23
Applicant: Merck Sharp & Dohme Corp.
Inventor： BERGER, Richard , CHANG, Lehua , EDMONDSON, Scott, D. , GOBLE, Stephen, D. , HARPER, Bart , KAR, Nam, Fung , KOPKA, Ihor, E. , LI, Bing , MORRIELLO, Gregori, J. , MOYES, Chris, R. , SHEN, Dong-ming , WANG, Liping , WENDT, Harvey , ZHU, Cheng
IPC: C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D495/04 , A61K31/4406 , A61P13/10
CPC classification number: C07D417/14 , C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D487/04 , C07D495/04
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公开(公告)号：EP2274296A1
公开(公告)日：2011-01-19
申请号：EP09726940.1
申请日：2009-03-23
Applicant: Merck Sharp & Dohme Corp.
Inventor： BERGER, Richard , CHANG, Lehua , EDMONDSON, Scott, D. , GOBLE, Stephen, D. , HARPER, Bart , KAR, Nam, Fung , KOPKA, Ihor, E. , LI, Bing , MORRIELLO, Gregori, J. , MOYES, Chris, R. , SHEN, Dong-ming , WANG, Liping , WENDT, Harvey , ZHU, Cheng
IPC: C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D495/04 , A61K31/4406 , A61P13/10
CPC classification number: C07D417/14 , C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D487/04 , C07D495/04
Abstract: The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
Abstract translation: 本发明提供了式I化合物，其药物组合物及其在治疗或预防由β3-肾上腺素受体激活介导的疾病中的使用方法。
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公开(公告)号：EP2276756B9
公开(公告)日：2012-08-15
申请号：EP09726601.9
申请日：2009-04-02
Applicant: Merck Sharp & Dohme Corp.
Inventor： BERGER, Richard , CHANG, Lehua , EDMONDSON, Scott, D. , GOBLE, Stephen, D. , HA, Sookhee, Nicole , KAR, Nam, Fung , KOPKA, Ihor, E. , LI, Bing , MORRIELLO, Gregori, J. , MOYES, Chris, R. , SHEN, Dong-Ming , WANG, Liping , ZHU, Cheng
IPC: C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04 , C07D487/04 , A61P13/00 , A61K31/4178 , A61K31/506
CPC classification number: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
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6.发明授权HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS 有权羟基甲基ALSβ3肾上腺素能REZEPTORAGONISTEN
公开(公告)号：EP2276756B1
公开(公告)日：2011-11-30
申请号：EP09726601.9
申请日：2009-04-02
Applicant: Merck Sharp & Dohme Corp.
Inventor： BERGER, Richard , CHANG, Lehua , EDMONDSON, Scott, D. , GOBLE, Stephen, D. , HA, Sookhee, Nicole , KAR, Nam, Fung , KOPKA, Ihor, E. , LI, Bing , MORRIELLO, Gregori, J. , MOYES, Chris, R. , SHEN, Dong-Ming , WANG, Liping , ZHU, Cheng
IPC: C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04 , C07D487/04 , A61P13/00 , A61K31/4178 , A61K31/506
CPC classification number: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
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