专利检索 ap:("Merus N.V.") AND inv:"TACKEN, Paulus Johannes" 第 1 页

1.

发明公开
BINDING MOLECULES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL 审中-公开

公开(公告)号：EP3649154A1

公开(公告)日：2020-05-13

申请号：EP18749179.0

申请日：2018-07-06

申请人： Merus N.V.

发明人： GEUIJEN, Cecilia Anna Wilhelmina , KLOOSTER, Rinse , DE KRUIF, Cornelis Adriaan , TACKEN, Paulus Johannes , THROSBY, Mark , LOGTENBERG, Ton

IPC分类号： C07K16/28 , C07K16/46 , A61K39/395

2.

发明公开
BINDING MOLECULES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL 审中-公开

公开(公告)号：EP3515951A1

公开(公告)日：2019-07-31

申请号：EP17785041.9

申请日：2017-09-22

申请人： Merus N.V.

发明人： GEUIJEN, Cecilia Anna Wilhelmina , THROSBY, Mark , DE KRUIF, Cornelis Adriaan , KLOOSTER, Rinse , TACKEN, Paulus Johannes , LOGTENBERG, Ton

IPC分类号： C07K16/46 , C07K16/28 , A61P35/00 , C07K16/12

3.

发明公开
BINDING MOLECULES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL 审中-实审

公开(公告)号：EP4342912A2

公开(公告)日：2024-03-27

申请号：EP23214705.8

申请日：2017-09-22

申请人： Merus N.V.

发明人： GEUIJEN, Cecilia Anna Wilhelmina , THROSBY, Mark , DE KRUIF, Cornelis Adriaan , KLOOSTER, Rinse , TACKEN, Paulus Johannes , LOGTENBERG, Ton

IPC分类号： C07K16/12

摘要： The invention provides means and methods of stimulating activity of a member of the TNF receptor superfamily on a cell. The invention also provides binding molecules such as antibodies that comprises at least two antigen binding sites, wherein a first antigen binding site can bind an extracellular part of said member and a second antigen binding site can bind an extracellular part of a second (different) membrane protein.

4.

发明公开
ANTIBODIES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL 审中-公开

公开(公告)号：EP3649156A1

公开(公告)日：2020-05-13

申请号：EP18749181.6

申请日：2018-07-06

申请人： Merus N.V.

发明人： GEUIJEN, Cecilia Anna Wilhelmina , KLOOSTER, Rinse , DE KRUIF, Cornelis Adriaan , TACKEN, Paulus Johannes , THROSBY, Mark , LOGTENBERG, Ton

IPC分类号： C07K16/28 , C07K16/12 , C07K16/46

5.

发明公开
BISPECIFIC ANTI PD1-ANTI TIM3 ANTIBODIES 审中-公开

公开(公告)号：EP3649155A1

公开(公告)日：2020-05-13

申请号：EP18749180.8

申请日：2018-07-06

申请人： Merus N.V.

发明人： GEUIJEN, Cecilia Anna Wilhelmina , KLOOSTER, Rinse , DE KRUIF, Cornelis Adriaan , TACKEN, Paulus Johannes , THROSBY, Mark , LOGTENBERG, Ton

IPC分类号： C07K16/28 , A61K39/00

6.

发明公开
BINDING MOLECULES THAT MODULATE A BIOLOGICAL ACTIVITY EXPRESSED BY A CELL 审中-实审

公开(公告)号：EP4342912A3

公开(公告)日：2024-05-22

申请号：EP23214705.8

申请日：2017-09-22

申请人： Merus N.V.

发明人： GEUIJEN, Cecilia Anna Wilhelmina , THROSBY, Mark , DE KRUIF, Cornelis Adriaan , KLOOSTER, Rinse , TACKEN, Paulus Johannes , LOGTENBERG, Ton

IPC分类号： C07K16/46 , C07K16/28 , A61P35/00 , C07K16/12

CPC分类号： C07K16/1282 , C07K16/2827 , C07K16/2875 , C07K16/2878 , C07K2317/3120130101 , C07K2317/5520130101 , C07K2317/7420130101 , C07K2317/7520130101 , C07K2317/7620130101 , A61P35/00 , C07K2317/3320130101

摘要： The invention provides means and methods of stimulating activity of a member of the TNF receptor superfamily on a cell. The invention also provides binding molecules such as antibodies that comprises at least two antigen binding sites, wherein a first antigen binding site can bind an extracellular part of said member and a second antigen binding site can bind an extracellular part of a second (different) membrane protein.