摘要:
A method for treating a desired volume of tissue using HIFU or other energy modality to ablate a pattern of elemental treatment volumes each having a volume that is greater than that of the focal zone of the HIFU transducer but smaller than the overall volume of the desired treatment volume. In one embodiment, the pattern of elemental treatment volumes are arranged to form a shell which partially or wholly encapsulates the desired volume of tissue, which then necroses in situ due to effects other than direct HIFU damage (including some combination of ischemia, thermal conduction, inflammation, apoptosis, etc.). The necrosed tissue remains in the body and is subsequently resorbed and/or healed via normal body mechanisms.
摘要:
An applicator for providing HIFU therapy to a patient includes a HIFU transducer that is rotatably coupled to a frame. In one embodiment, the rotatable coupling is configured such that the HIFU transducer can be mechanically oriented to position a focal zone of the HIFU transducer at any desired location in a treatment volume radially outward from a longitudinal axis of the applicator while the HIFU transducer remains within a housing that is not more than a defined percentage (e.g., 50%) larger than the maximum diameter of the HIFU transducer. In one embodiment, the HIFU transducer is rotatably coupled to the frame with a ball and socket joint. In another embodiment, the HIFU transducer is rotatably coupled to the frame with an offset gimble assembly. A pair of linear actuators and drive shafts engage the HIFU transducer to orient HIFU transducer in a desired direction.