公开(公告)号：EP4043466A1

公开(公告)日：2022-08-17

申请号：EP22165237.3

申请日：2019-01-29

申请人： Mirati Therapeutics, Inc.

发明人： MARX, Matthew, Arnold ,  LEE, Matthew, Randolph ,  BOBINSKI, Thomas, P. ,  BURNS, Aaron, Craig ,  ARORA, Nidhi ,  CHRISTENSEN, James, Gail ,  KETCHAM, John. Michael

IPC分类号： C07D487/04 ,  A61P35/00 ,  A61K31/519

摘要： The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.