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公开(公告)号：EP3710439A1
公开(公告)日：2020-09-23
申请号：EP18879484.6
申请日：2018-11-14
发明人： BLAKE, James, F. , BURGESS, Laurence, E. , CHICARELLI, Mark, Joseph , CHRISTENSEN, James, Gail , COOK, Adam , FELL, Jay, Bradford , FISCHER, John, P. , MARX, Matthew, Arnold , MEJIA, Macedonio, J. , SAVECHENKOV, Pavel , VIGERS, Guy, P.A. , SMITH, Christopher, Ronald , RODRIGUEZ, Martha, E.
IPC分类号： C07D401/06 , C07D401/14
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公开(公告)号：EP4358963A1
公开(公告)日：2024-05-01
申请号：EP22829140.7
申请日：2022-06-21
发明人： KETCHAM, John, Michael , SMITH, Christopher, Ronald , MARX, Matthew, Arnold , WANG, Xiaolun , BURNS, Aaron, Craig , KULYK, Svitlana , IVETAC, Anthony , LAWSON, John, David
IPC分类号： A61K31/502 , A61K31/5025 , C07D237/26 , A61P35/00
CPC分类号： A61P35/00 , C07D471/04 , C07D519/00 , C07D401/12 , C07D237/34 , C07D491/107 , C07D487/10 , C07D403/04 , C07D498/04 , C07D491/08 , C07D487/08 , C07D405/12
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公开(公告)号：EP4322945A2
公开(公告)日：2024-02-21
申请号：EP22788931.8
申请日：2022-04-14
发明人： BURNS, Aaron, Craig , CHRISTENSEN, James, Gail , LAWSON, John, David , MARX, Matthew, Arnold , SMITH, Christopher, Ronald
IPC分类号： A61K31/428 , A61K31/496 , A61K31/519
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公开(公告)号：EP4087573A1
公开(公告)日：2022-11-16
申请号：EP20912875.0
申请日：2020-06-30
发明人： MARX, Matthew, Arnold , CHRISTENSEN, James, Gail , SMITH, Christopher, Ronald , FISCHER, John, P. , BURNS, Aaron, Craig
IPC分类号： A61K31/506 , A61K31/519
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公开(公告)号：EP3880208A1
公开(公告)日：2021-09-22
申请号：EP19886028.0
申请日：2019-05-14
发明人： MARX, Matthew, Arnold , BOBINSKI, Thomas, P. , BURNS, Aaron, Craig , GAUDINO, John , HAAS, Julia , KETCHAM, John, Michael , LAWSON, John, David , NEWHOUSE, Brad , PAJK, Spencer , SMITH, Christopher, Ronald , TANG, Tony, P.
IPC分类号： A61K31/519 , C07D471/04 , C07D519/00
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公开(公告)号：EP3790551A1
公开(公告)日：2021-03-17
申请号：EP19799195.3
申请日：2019-05-06
发明人： MARX, Matthew, Arnold , LEE, Matthew, Randolph , BLAKE, James, F. , CHICARELLI, Mark, Joseph , FELL, Jay, Bradford , FISHER, John, P. , HICKEN, Erik, James , SAVENCHENKOV, Pavel , TANG, Tony , VIGERS, Guy, P.A. , ZECCA, Henry, J.
IPC分类号： A61K31/538 , C07D265/36 , A61P35/00
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公开(公告)号：EP4304720A1
公开(公告)日：2024-01-17
申请号：EP22713826.0
申请日：2022-03-11
发明人： BOBINSKI, Thomas, P. , SMITH, Christopher, Ronald , MARX, Matthew, Arnold , KETCHAM, John, Michael , BURNS, Aaron, Craig , LAWSON, John, David , KULYK, Svitlana , KUEHLER, Jon , IVETAC, Anthony
IPC分类号： A61P31/00 , A61P43/00 , C07D401/10 , C07D401/14 , C07D403/10 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D495/04 , A61K31/498
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公开(公告)号：EP4182313A1
公开(公告)日：2023-05-24
申请号：EP21843038.7
申请日：2021-02-25
发明人： WANG, Xiaolun , BURNS, Aaron, Craig , CHRISTENSEN, James, Gail , KETCHAM, John, Michael , LAWSON, John, David , MARX, Matthew, Arnold , SMITH, Christopher, Ronald , ALLEN, Shelley , BLAKE, James, Francis , CHICARELLI, Mark, Joseph , DAHLKE, Joshua, Ryan , DAI, Donghua , FELL, Jay, Bradford , FISCHER, John, Peter , MEJIA, Macedonio, J. , NEWHOUSE, Brad , NGUYEN, Phong , O'LEARY, Jacob, Matthew , PAJK, Spencer , RODRIGUEZ, Martha, E. , SAVECHENKOV, Pavel , TANG, Tony, P. , VIGERS, Guy, P.A. , ZHAO, Qian , KAHN, Dean Russell , GAUDINO, John , HILTON, Michael, Christopher
IPC分类号： C07D471/04 , A61K31/519 , A61P35/00
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公开(公告)号：EP4043466A1
公开(公告)日：2022-08-17
申请号：EP22165237.3
申请日：2019-01-29
发明人： MARX, Matthew, Arnold , LEE, Matthew, Randolph , BOBINSKI, Thomas, P. , BURNS, Aaron, Craig , ARORA, Nidhi , CHRISTENSEN, James, Gail , KETCHAM, John. Michael
IPC分类号： C07D487/04 , A61P35/00 , A61K31/519
摘要： The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
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公开(公告)号：EP4028388A1
公开(公告)日：2022-07-20
申请号：EP20781175.3
申请日：2020-09-11
发明人： BOBINSKI, Thomas, P. , SMITH, Christopher, Ronald , MARX, Matthew, Arnold , KETCHAM, John, Michael , BURNS, Aaron, Craig , LAWSON, John, David , KULYK, Svitlana , KUEHLER, Jon , IVETAC, Anthony
IPC分类号： C07D237/32 , C07D401/10 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/10 , C07D405/14 , C07D409/14 , C07D413/10 , C07D417/10 , C07D417/14 , C07D471/04 , C07D471/14 , C07D487/04 , C07D498/04
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