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1.发明公开USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES 审中-公开维多利亚州密克罗尼西亚内华达州麻省理工学院脱氧核糖核酸
公开(公告)号：EP2968672A1
公开(公告)日：2016-01-20
申请号：EP14725270.4
申请日：2014-03-13
发明人： ROSS, Jeffrey , SEETAPUN, Dominique
CPC分类号： A61L27/3808 , A61L27/3633 , A61L27/3683 , A61L27/3804 , A61L27/3834 , A61L27/48 , A61L27/507 , C12N5/069
摘要： The invention provides a method for maintaining capillary lumen diameter, reducing a decrease in capillary vessel lumen diameter or expanding capillary vessel lumen diameter in a re-endothelialized decellularized organ or tissue graft with an intact extracellular matrix vascular network. The method is based on administration of endothelial cells and microparticles to the decellularized ECM.
摘要翻译： 本发明提供了一种用于维持毛细血管内径直径，减少毛细血管管腔直径的减少或在具有完整的细胞外基质血管网络的再内皮化脱细胞器官或组织移植物中扩张毛细管管腔直径的方法。 该方法基于将内皮细胞和微粒施用于脱细胞的ECM。
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公开(公告)号：EP3908339A1
公开(公告)日：2021-11-17
申请号：EP20703611.2
申请日：2020-01-07
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公开(公告)号：EP3274007B1
公开(公告)日：2020-09-30
申请号：EP16730926.9
申请日：2016-03-24
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公开(公告)号：EP2968672B1
公开(公告)日：2019-02-06
申请号：EP14725270.4
申请日：2014-03-13
发明人： ROSS, Jeffrey , SEETAPUN, Dominique
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公开(公告)号：EP3274007A1
公开(公告)日：2018-01-31
申请号：EP16730926.9
申请日：2016-03-24
摘要： A method to provide an inflated decellularized extracellular matrix of a mammalian organ or a vascularized portion thereof, or a mammalian vascularized tissue or a vascularized portion thereof, an inflated decellularized extracellular matrix of a mammalian organ or a vascularized portion thereof, or a mammalian vascularized tissue or a vascularized portion thereof, and uses thereof, are provided.
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