公开(公告)号：EP3954711A1

公开(公告)日：2022-02-16

申请号：EP20788397.6

申请日：2020-04-06

申请人： Green Cross Corporation ,  Mogam Institute for Biomedical Research

发明人： PARK, Jae Chan ,  SONG, Eun Jung ,  LIM, So Jung ,  LEE, Jae-Chul ,  KWON, Hae Naem ,  LEE, Su A ,  LIM, Ok Jae ,  KIM, Mun Kyung ,  CHO, Hyun Jung ,  KIM, Gil-Jung ,  LEE, Jee Won ,  KIM, Sung Keun ,  WON, Jong Wha ,  JANG, Shin A

IPC分类号： C07K16/30 ,  C07K16/28 ,  A61P35/00

摘要： The present invention relates to a bispecific anti-GPNMB/anti-CD3 antibody specifically binding to CD3 and GPNMB, and the use thereof. Particularly, the bispecific antibody shows high affinity and specificity to CD3 and GPNMB and thus can induce death of cancer cells expressing GPNMB and inhibit proliferation thereof. Therefore, the bispecific antibody can be used as an effective therapeutic agent for cancers expressing GPNMB.

公开(公告)号：EP4174084A1

公开(公告)日：2023-05-03

申请号：EP21828260.6

申请日：2021-05-07

申请人： Mogam Institute for Biomedical Research

发明人： KIM, Dong Sik ,  JANG, Shin A ,  HAN, Young Woo ,  LEE, Su A ,  KIM, Woo Hyun

IPC分类号： C07K16/10 ,  A61P31/14 ,  A61K39/00

摘要： The present invention relates to an anti-respiratory syncytial virus (RSV) antibody and a pharmaceutical composition comprising the same, and particularly, to an anti-RSV antibody specifically binding to an F-protein of RSV, and a pharmaceutical composition for use in preventing or treating an RSV infection. The anti-RSV antibody according to the present invention can effectively prevent RSV infection and has excellent efficacy for alleviating and treating symptoms of RSV infection.