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3.发明公开
公开(公告)号：EP3424490A1
公开(公告)日：2019-01-09
申请号：EP17305881.9
申请日：2017-07-06
发明人： DAVID, Hélène
摘要： The present invention relates to low concentration synergistic Xenon-Argon gas mixtures as organ protectant, in particular as neuroprotectant. Specifically, the present invention relates to a pharmaceutical composition comprising a gas mixture of xenon and argon for use as organ protectant, in particular as neuroprotectant, wherein
- the volume proportion of xenon is between 5 and 25%,
- the volume proportion of argon is between 5 and 25%, and
- the pharmaceutical composition further comprises a gas complement to reach 100% volume proportion.
More specifically, the pharmaceutical composition of the invention is useful for treating and/or preventing and/or slowing the degradation of the structure and/or function of organ cells (in particular neurons), in mammals suffering a decompression accident, neonatal hypoxia-ischemia, stroke, traumatic brain injury, cardiac arrest, renal dysfunction, neurocognitive disorders, post-traumatic stress disorder (PTSD), neurodegenerative diseases, and psychiatric disorders.-
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公开(公告)号：EP3424550A1
公开(公告)日：2019-01-09
申请号：EP17305878.5
申请日：2017-07-06
发明人： DAVID, Hélène
摘要： The present invention relates to low concentration synergistic Xenon-Argon gas mixtures argon for use in a method for preventing and/or treating ischemic insults, wherein
- the volume proportion of xenon is between 5 and 20 %,
- the volume proportion of argon is between 5 and 20 %, and
- the pharmaceutical composition further comprises a gas complement to reach 100 % volume proportion,
- the method includes comprises restoration of blood flow and the gas mixture is administered to the patient before, during, or after blood flow restoration.
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