公开(公告)号：EP1984348A2

公开(公告)日：2008-10-29

申请号：EP07750407.4

申请日：2007-02-09

申请人： Multi Formulations Ltd.

发明人： HEUER, Marvin, A.

IPC分类号： C07D339/02 ,  C07D341/00 ,  C07D409/00

CPC分类号： A61K31/385 ,  A23L33/12 ,  A23L33/30 ,  A23V2002/00 ,  A23V2250/026 ,  A23V2200/02 ,  A23V2200/332

摘要： The invention provides a method for reducing esophageal irritation associated with alpha-lipoic acid upon oral administration through the use of the trometamol salt of alpha-lipoic acid. The present invention also provides for the increased solubility of alpha-lipoic acid through the use of the trometamol salt of alpha-lipoic acid. The trometamol salt of alpha-lipoic acid, as provided by the present invention can be used as a substitute for regular, non-salt forms alpha-lipoic acid in dietary supplement compositions.