公开(公告)号：EP1618178A2

公开(公告)日：2006-01-25

申请号：EP04749924.9

申请日：2004-04-21

申请人： Musculoskeletal Transplant Foundation ,  Gomes, Katherine, A. ,  Sunwoo, Moon Hae ,  Gertzman, Arthur, A. ,  Tomford, William, W.

发明人： GOMES, Katherine, A. ,  SUNWOO, Moon Hae ,  GERTZMAN, Arthur, A. ,  TOMFORD, William, W.

IPC分类号： C12N1/00

CPC分类号： A61F2/28 ,  A61B17/00491 ,  A61F2/30744 ,  A61F2/30756 ,  A61F2/3094 ,  A61F2/3859 ,  A61F2002/2817 ,  A61F2002/2867 ,  A61F2002/30062 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30759 ,  A61F2002/30764 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2310/00365 ,  A61F2310/00383 ,  A61K35/28 ,  A61K35/32 ,  A61K38/18 ,  A61K38/28 ,  A61L27/20 ,  A61L27/24 ,  A61L27/3612 ,  A61L27/3654 ,  A61L27/3683 ,  A61L27/3817 ,  A61L27/3821 ,  A61L27/3834 ,  A61L27/3852 ,  A61L27/48 ,  A61L27/56 ,  A61L27/58 ,  A61L2430/06 ,  A61K2300/00 ,  C08L5/08

摘要： The invention is directed toward a sterile cartilage defect implant material comprising milled lyophilized allograft cartilage pieces ranging from 0.01 mm to 1.0 mm in size in a bioabsorbable carrier taken from a group consisting of sodium hyaluronate, hyaluronic acid and its derivatives, gelatin, collagen, chitosan, alginate, buffered PBS, Dextran or polymers with allogenic chondrocytes or bone marrow cells in an amount exceeding the natural occurrence of same in hyaline cartilage and adding a cell growth additive.

公开(公告)号：EP1618178B1

公开(公告)日：2008-07-16

申请号：EP04749924.9

申请日：2004-04-21

申请人： Musculoskeletal Transplant Foundation

发明人： TRUNCALE, Katherine, A. ,  SUNWOO, Moon Hae ,  GERTZMAN, Arthur, A. ,  TOMFORD, William, W.

IPC分类号： A61K35/32

CPC分类号： A61F2/28 ,  A61B17/00491 ,  A61F2/30744 ,  A61F2/30756 ,  A61F2/3094 ,  A61F2/3859 ,  A61F2002/2817 ,  A61F2002/2867 ,  A61F2002/30062 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30759 ,  A61F2002/30764 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2310/00365 ,  A61F2310/00383 ,  A61K35/28 ,  A61K35/32 ,  A61K38/18 ,  A61K38/28 ,  A61L27/20 ,  A61L27/24 ,  A61L27/3612 ,  A61L27/3654 ,  A61L27/3683 ,  A61L27/3817 ,  A61L27/3821 ,  A61L27/3834 ,  A61L27/3852 ,  A61L27/48 ,  A61L27/56 ,  A61L27/58 ,  A61L2430/06 ,  A61K2300/00 ,  C08L5/08

摘要： The invention is directed toward a sterile cartilage defect implant material comprising milled lyophilized allograft cartilage pieces ranging from 0.01 mm to 1.0 mm in size in a bioabsorbable carrier taken from a group consisting of sodium hyaluronate, hyaluronic acid and its derivatives, gelatin, collagen, chitosan, alginate, buffered PBS, Dextran or polymers with allogenic chondrocytes or bone marrow cells in an amount exceeding the natural occurrence of same in hyaline cartilage and adding a cell growth additive.