公开(公告)号：EP3623482A1

公开(公告)日：2020-03-18

申请号：EP19205988.9

申请日：2015-05-13

申请人： Myriad Genetics, Inc.

发明人： STONE, Steven ,  GUTIN, Alexander ,  REID, Julia

IPC分类号： C12Q1/68

摘要： Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.

公开(公告)号：EP2739753A2

公开(公告)日：2014-06-11

申请号：EP12819493.3

申请日：2012-08-03

申请人： Myriad Genetics, Inc. ,  Gutin, Alexander ,  Jammulapati, Srikanth ,  Wagner, Susanne ,  Reid, Julia E. ,  Flake, Darl

发明人： GUTIN, Alexander ,  JAMMULAPATI, Srikanth ,  WAGNER, Susanne ,  REID, Julia ,  FLAKE, Darl

IPC分类号： C12Q1/68 ,  C12N15/11

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158

摘要： Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided.

公开(公告)号：EP2382331A1

公开(公告)日：2011-11-02

申请号：EP10729525.5

申请日：2010-01-07

申请人： Myriad Genetics, Inc.

发明人： STONE, Steve ,  GUTIN, Alexander ,  WAGNER, Susanne ,  REID, Julia

IPC分类号： C12Q1/68 ,  G01N33/53

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/154 ,  C12Q2600/158 ,  C12Q2600/178 ,  G01N33/574 ,  G01N2800/56

摘要： Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.

摘要翻译： 提供了使用生物标志物预测患者癌症复发风险的生物标志物和方法。

公开(公告)号：EP3686288A1

公开(公告)日：2020-07-29

申请号：EP20162059.8

申请日：2015-08-17

申请人： Myriad Genetics, Inc.

发明人： ABKEVICH, Victor ,  TIMMS, Kirsten ,  GUTIN, Alexander ,  REID, Julia

IPC分类号： C12Q1/68

摘要： This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell ( e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.

公开(公告)号：EP3180447B1

公开(公告)日：2020-03-11

申请号：EP15757372.6

申请日：2015-08-17

申请人： Myriad Genetics, Inc.

发明人： ABKEVICH, Victor ,  TIMMS, Kirsten ,  GUTIN, Alexander ,  REID, Julia

IPC分类号： C12Q1/68

公开(公告)号：EP3143160A1

公开(公告)日：2017-03-22

申请号：EP15727137.0

申请日：2015-05-13

申请人： Myriad Genetics, Inc. ,  Stone, Steven ,  Gutin, Alexander ,  Reid, Julia

发明人： STONE, Steven ,  GUTIN, Alexander ,  REID, Julia

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158

摘要： Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.

摘要翻译： 提供了使用生物标志物在患者中分类癌症的生物标志物和方法（例如，预测癌症特异性死亡或癌症复发的风险）。

公开(公告)号：EP2920322A1

公开(公告)日：2015-09-23

申请号：EP13795976.3

申请日：2013-11-15

申请人： Myriad Genetics, Inc. ,  Stone, Steve ,  Gutin, Alexander ,  Wagner, Susanne ,  Reid, Julia E.

发明人： STONE, Steven ,  GUTIN, Alexander ,  WAGNER, Susanne ,  REID, Julia

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158

摘要： Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.

公开(公告)号：EP4234711A2

公开(公告)日：2023-08-30

申请号：EP23160447.1

申请日：2015-08-17

申请人： Myriad Genetics, Inc.

发明人： ABKEVICH, Victor ,  TIMMS, Kirsten ,  GUTIN, Alexander ,  REID, Julia

IPC分类号： C12Q1/68

摘要： This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.

公开(公告)号：EP2611941A2

公开(公告)日：2013-07-10

申请号：EP11822498.9

申请日：2011-08-30

申请人： Myriad Genetics, Inc. ,  Stone, Steve ,  Gutin, Alexander ,  Wagner, Susanne ,  Reid, Julia E.

发明人： STONE, Steven ,  GUTIN, Alexander ,  WAGNER, Susanne ,  REID, Julia

IPC分类号： C12Q1/68 ,  C12N15/11 ,  G06F19/10

CPC分类号： C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16 ,  G06F19/20

摘要： Biomarkers and methods using the biomarkers for molecular detection and classification of disease and, particularly, molecular markers for cancer diagnosis and prognosis and methods of use thereof are provided.

摘要翻译： 提供了使用生物标志物进行分子检测和分类疾病的生物标志物和方法，特别是用于癌症诊断和预后的分子标记物及其使用方法。

公开(公告)号：EP4234711A3

公开(公告)日：2023-09-20

申请号：EP23160447.1

申请日：2015-08-17

申请人： Myriad Genetics, Inc.

发明人： ABKEVICH, Victor ,  TIMMS, Kirsten ,  GUTIN, Alexander ,  REID, Julia

IPC分类号： C12Q1/68 ,  A61P35/00 ,  C12Q1/6886

摘要： This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.