公开(公告)号：EP0625524A3

公开(公告)日：1995-08-02

申请号：EP94107506.1

申请日：1994-05-13

申请人： NAKANO VINEGAR CO., LTD.

发明人： Okamoto, yoshio ,  Enomoto, Naoki ,  Furukawa, Sachiko ,  Ogasawara, Yasushi ,  Akano. Hirofumi ,  Kawamura, Yoshiya

IPC分类号： C08B37/00 ,  C12N11/10 ,  C07B57/00 ,  C08B33/02 ,  B01J20/32

CPC分类号： B01J20/3274 ,  B01J20/103 ,  B01J20/28004 ,  B01J20/28083 ,  B01J20/28085 ,  B01J20/29 ,  B01J20/3092 ,  B01J20/3204 ,  B01J20/3217 ,  B01J20/3219 ,  B01J20/3227 ,  B01J20/3246 ,  B01J20/3257 ,  B01J20/3259 ,  B01J20/3261 ,  B01J20/3263 ,  B01J2220/4825 ,  B01J2220/54 ,  B01J2220/58 ,  C07B57/00 ,  C08B37/00

摘要： A novel substance having a main structure represented by the following Formula:

   Also disclosed are a method of producing the substance in which an oligosaccharide having a degree of polymerization from 3 to 10 is chemically bonded to a silane agent at the reducing terminal of the oligosaccharide, the oligosaccharide derivative obtained is polymerized to an average degree of polymerization from about 11 to about 500 with the action of an enzyme; and a method in which the aldehyde group present at the reducing terminal of an oligosaccharide having a degree of polymerization from 3 to 10 is oxidized with an oxidizing agent, and the saccharide chain of the oxidized product is polymerized to a degree of polymerization from about 11 to about 500 by the action of an enzyme, followed by the addition of an acid. The substance is excellent in solvent resistance and useful as a separating agent for chromatography, in particular, for the separation of chiral compounds.

公开(公告)号：EP0625524A2

公开(公告)日：1994-11-23

申请号：EP94107506.1

申请日：1994-05-13

申请人： NAKANO VINEGAR CO., LTD.

发明人： Okamoto, yoshio ,  Enomoto, Naoki ,  Furukawa, Sachiko ,  Ogasawara, Yasushi ,  Akano. Hirofumi ,  Kawamura, Yoshiya

IPC分类号： C08B37/00 ,  C12N11/10 ,  C07B57/00 ,  C08B33/02 ,  B01J20/32

CPC分类号： B01J20/3274 ,  B01J20/103 ,  B01J20/28004 ,  B01J20/28083 ,  B01J20/28085 ,  B01J20/29 ,  B01J20/3092 ,  B01J20/3204 ,  B01J20/3217 ,  B01J20/3219 ,  B01J20/3227 ,  B01J20/3246 ,  B01J20/3257 ,  B01J20/3259 ,  B01J20/3261 ,  B01J20/3263 ,  B01J2220/4825 ,  B01J2220/54 ,  B01J2220/58 ,  C07B57/00 ,  C08B37/00

摘要： A novel substance having a main structure represented by the following Formula:

   Also disclosed are a method of producing the substance in which an oligosaccharide having a degree of polymerization from 3 to 10 is chemically bonded to a silane agent at the reducing terminal of the oligosaccharide, the oligosaccharide derivative obtained is polymerized to an average degree of polymerization from about 11 to about 500 with the action of an enzyme; and a method in which the aldehyde group present at the reducing terminal of an oligosaccharide having a degree of polymerization from 3 to 10 is oxidized with an oxidizing agent, and the saccharide chain of the oxidized product is polymerized to a degree of polymerization from about 11 to about 500 by the action of an enzyme, followed by the addition of an acid.
The substance is excellent in solvent resistance and useful as a separating agent for chromatography, in particular, for the separation of chiral compounds.

摘要翻译： 具有由下式表示的主要结构的新物质：游离缺失所以盘是制造在其中具有3的聚合度至10的低聚糖的物质在还原末端化学键合到硅烷剂的方法 寡糖，将得到的糖链衍生物是从约11至与酶的作用大约500聚合以平均聚合度; 并且其中存在于具有3的聚合度至10的寡糖的还原性末端醛基在氧化剂氧化用的方法，以及氧化产物的糖链从约11聚合至聚合度 到通过酶的作用约500，通过添加酸，接着。 该物质具有优良的耐溶剂性和作为用于色谱的分离剂是有用的，特别是用于手性化合物的分离。