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    COMPLEX CRYSTALLINE SUGAR COMPRISING D-PSICOSE AND D-ALLOSE AND PROCESS FOR PRODUCTION OF THE SAME
    4.
    发明公开
    COMPLEX CRYSTALLINE SUGAR COMPRISING D-PSICOSE AND D-ALLOSE AND PROCESS FOR PRODUCTION OF THE SAME 有权
    COMPLEX，D-阿洛酮糖和D-阿洛糖含有结晶糖和方法及其生产

    公开(公告)号：EP1860195A4

    公开(公告)日：2011-10-19

    申请号：EP06715211

    申请日：2006-03-03

    申请人： UNIV KAGAWA NAT UNIV CORP ,  MATSUTANI KAGAKU KOGYO KK

    发明人： IZUMORI KEN ,  TOKUDA MASAAKI ,  TAKADA GORO ,  MORIMOTO KENJI

    IPC分类号： C12P19/02 ,  C12P19/24 ,  C12R1/38

    CPC分类号： C12P19/02 ,  C12P19/24

    摘要： Disclosed is a process for producing a crystalline sugar comprising D-psicose and D-allose. Also disclosed is a process for producing the sugar. A complex crystalline sugar comprising D-psicose and D-allose. The compositional ratio between D-psicose and D-allose in the sugar is about 1:1 to 1:4. A process for producing a complex crystalline sugar comprising D-psicose and D-allose, the process comprising producing a complex crystalline sugar comprising D-psicose and D-allose from a sugar solution containing D-psicose and p-allose and collecting the complex crystalline sugar. The solvent of the sugar solution used in the production of the complex crystalline sugar is water or a mixture of water and ethanol. The sugar solution containing D-psicose and D-allose is produced by a process comprising reacting D-psicose with L-rhamnose isomerase to convert D-psicose into D-allose. The L-rhamnose isomerase is derived from a strain (IPOD FERM BP-08593) belonging to Pseudomonas stutzeri.

    UTILIZATION OF THE FUNCTION OF RARE SUGAR AS PROMOTER FOR THE MIGRATION OF GLUCOKINASE FROM NUCLEUS TO CYTOPLASM
    5.
    发明公开
    UTILIZATION OF THE FUNCTION OF RARE SUGAR AS PROMOTER FOR THE MIGRATION OF GLUCOKINASE FROM NUCLEUS TO CYTOPLASM 审中-公开
    稀有糖的功能的一种手段用来提高核葡糖激酶的迁移关闭进入细胞质

    公开(公告)号：EP2111865A4

    公开(公告)日：2010-08-04

    申请号：EP07739883

    申请日：2007-03-27

    申请人： UNIV KAGAWA NAT UNIV CORP ,  MATSUTANI KAGAKU KOGYO KK

    发明人： TOKUDA MASAAKI ,  IZUMORI KEN ,  TOYODA YUKIYASU ,  MIWA ICHITOMO

    IPC分类号： A61K31/7004 ,  A23L1/30 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  C07H3/02

    CPC分类号： A61K31/121 ,  A23L33/10 ,  A23V2002/00 ,  A61K31/7004 ,  C07H3/02

    摘要： Screening for a glucokinase-activating substance among rare sugars and providing a composition for treating disordered conditions in association with glucokinase activity, the composition containing the glucokinase-activating substance as the active ingredient. A promoting agent of glucokinase transfer from nucleus to cytoplasm, the promoting agent containing D-psicose and/or D-tagatose as the active ingredient, or a composition for preventing the onset of disordered conditions in association with glucokinase activity or for therapeutically treating the disordered conditions, which is in a form selected from a group consisting of food additives, food materials, drinks and foods, health drinks and foods, pharmaceutical product and feeds in blend with D-psicose and/or D-tagatose as the active ingredient for use in preventing the onset of disordered conditions in association with glucokinase activity or for therapeutically treating the disordered conditions. The disordered conditions in association with glucokinase activity are selected from impaired glucose tolerance, type 2 diabetes mellitus, insulin resistance, abnormal lipidemia, the metabolic syndrome and obesity. The composition is in a pharmaceutical form, and contains D-psicose and/or D-tagatose together with one or more pharmaceutically acceptable carriers.