公开(公告)号：EP2769321A4

公开(公告)日：2015-05-13

申请号：EP12841790

申请日：2012-10-19

申请人： NESTEC SA

发明人： PRINCEN FRED ,  LOCKTON STEVEN ,  CRONER LISA J ,  FLETCHER FREDERICK A ,  STOCKFISCH THOMAS ,  SINGH SHARAT

IPC分类号： C12Q1/68 ,  G01N33/48 ,  G01N33/53 ,  G06F19/00

CPC分类号： G06F19/3431 ,  C12Q1/6883 ,  C12Q2600/112 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/54306 ,  G01N33/6854 ,  G01N33/6893 ,  G01N2333/4737 ,  G01N2333/49 ,  G01N2333/70525 ,  G01N2333/70542 ,  G01N2333/775 ,  G01N2800/065 ,  G01N2800/60 ,  G06F19/18 ,  G06F19/24 ,  G16H50/30 ,  Y02A90/24 ,  Y02A90/26

摘要： The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (IBD) and subtypes such as ulcerative colitis (UC) and Crohn's disease (CD) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of IBD versus non-IBD, to rule out IBD that is inconclusive for CD and UC, and to differentiate between CD and UC with increased accuracy.