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公开(公告)号:EP3201225A4
公开(公告)日:2018-05-23
申请号:EP15848061
申请日:2015-10-02
发明人: LIU ZHONGHAO , DING XUNSHAN
IPC分类号: C07K14/575 , A61K38/22 , A61P3/04 , A61P3/06 , A61P3/10
CPC分类号: A61K38/22 , A61P3/04 , A61P3/06 , A61P3/10 , C07K14/575 , C07K2319/00 , C07K2319/30 , C07K2319/31 , C07K2319/50 , G01N33/92
摘要: Methods and compositions for reducing one or more of triglyceride levels, total cholesterol levels and LDL cholesterol levels in a subject are provided. The methods include administering a fragment of ANGPTL8 to a subject having or at risk of developing elevated triglyceride levels, elevated total cholesterol levels and/or elevated LDL cholesterol levels.