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1.
公开(公告)号:EP0667768A1
公开(公告)日:1995-08-23
申请号:EP93923058.0
申请日:1993-10-26
发明人: ITOH, Junpei , MIYAZAKI, Osamu , EKIMOTO, Hisao , KOYAMA, Michinori , SAINO, Tetsushi , KANGAS, Lauri , WARRI, Anni
IPC分类号: A61K31
CPC分类号: A61K31/138 , A61K31/00 , A61K31/135 , A61K31/56 , A61K31/57 , A61K2300/00
摘要: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
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2.
公开(公告)号:EP0667768B1
公开(公告)日:1999-03-03
申请号:EP93923058.7
申请日:1993-10-26
发明人: Itoh, Junpei , MIYAZAKI, Osamu , EKIMOTO, Hisao , KOYAMA, Michinori , SAINO, Tetsushi , KANGAS, Lauri , WARRI, Anni , GRANBERG Christer
IPC分类号: A61K31/00 , A61K31/135
CPC分类号: A61K31/138 , A61K31/00 , A61K31/135 , A61K31/56 , A61K31/57 , A61K2300/00
摘要: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
摘要翻译: 公开了含有非甾族抗雌激素或其药学上可接受的盐和糖皮质激素的产品,作为用于自身免疫性疾病的治疗的组合制剂。
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3.METHOD FOR PREDICTING ANTITUMOR EFFICACY OF HSP90 INHIBITOR IN CANCER TREATMENT 审中-公开
标题翻译: VERFAHREN ZUR PROGNOSE DER ANTITUMORWIRKSAMKEIT EINES HSP90-HEMMERS在DER KREBSBEHANDLUNG公开(公告)号:EP3086119A1
公开(公告)日:2016-10-26
申请号:EP14871790.3
申请日:2014-12-03
IPC分类号: G01N33/574 , C12Q1/48
CPC分类号: G01N33/5011 , C12Q1/485 , G01N33/574 , G01N2333/91205 , G01N2333/91215
摘要: A method for determining sensitivity of a tumor to a HSP90 inhibitor, including:
measuring a phosphorylation level of Akt or a phosphorylation level of ERK in a tissue of the tumor from a patient.摘要翻译: 用于确定肿瘤对HSP90抑制剂的敏感性的方法,包括:测量来自患者的肿瘤组织中Akt的磷酸化水平或ERK的磷酸化水平。
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公开(公告)号:EP3086119B1
公开(公告)日:2019-06-26
申请号:EP14871790.3
申请日:2014-12-03
IPC分类号: G01N33/574 , C12Q1/48
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