公开(公告)号：EP1326672A4

公开(公告)日：2007-03-07

申请号：EP01981600

申请日：2001-10-17

申请人： NMT MEDICAL INC

发明人： FORDE SEAN T ,  OPOLSKI STEVEN W

IPC分类号： A61B17/00 ,  A61B17/12 ,  A61F2/01 ,  A61F2/84 ,  A61M29/00 ,  A61F2/06 ,  A61F2/24

CPC分类号： A61B17/0057 ,  A61B17/00234 ,  A61B17/12022 ,  A61B2017/00575 ,  A61B2017/00619 ,  A61B2017/1205 ,  A61F2/01 ,  A61F2/95 ,  A61F2/962 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2002/9505 ,  A61F2002/9528 ,  A61F2230/005 ,  A61F2230/0067

摘要： The over-the-wire interlock attachment/detachment mechanism includes a cylindrical lock receiving section of a small diameter attached to an implantable medical device such as a blood clot filter, a stent, or a septal occluder. This cylindrical lock receiving section has a plurality of spaced, curved cutouts to receive both the guide fingers and contoured locking fingers formed on a cylindrical locking section. The locking fingers are angled outwardly from the cylindrical body of the cylindrical locking section, and are moved inwardly into engagement with the curved cutouts of the cylindrical lock receiving section by a sheath which slides over the cylindrical locking section or other suitable operator.

公开(公告)号：EP1487353A4

公开(公告)日：2008-04-16

申请号：EP03716812

申请日：2003-03-25

申请人： NMT MEDICAL INC

发明人： PEAVEY TODD A ,  FORDE SEAN T ,  CHANDUSZKO ANDRZEJ J ,  CALLAGHAN DAVID J

IPC分类号： A61B17/00 ,  A61B20060101 ,  A61B17/08 ,  A61B17/12

CPC分类号： A61B17/0057 ,  A61B17/083 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00867

摘要： The present invention provides a patent foramen ovale (PFO) closure clip. The clips of the present invention include two closure members joined by at least two spaced central connecting members. Each of the at least two spaced central connecting members is attached to each closure member at a location on a periphery of the closure member. The clips are designed such that the at least two central connecting members extend through the inclined PFO tunnel and the two closure members compress the overlapping layers of septal tissue, i.e. septum primum and septum secundum, together to close the PFO tunnel. The clips of the present invention may be formed of various materials. In at least some embodiments, the clips are formed of metals, nonmetallic materials, bioabsorbable polymers, spring steel, shape memory materials, bioabsorbable shape memory polymers, or combinations thereof. The clips of the present invention take various forms depending, in part, upon the distribution of force required to close a given PFO. Thus, in some embodiments, the closure members include arcuate peaks. In other embodiments, the closure members include loops. In still other embodiments, the closure members include prongs. In yet other embodiments, the closure members include centering elements for centering the device in the desired delivery location. In at least some embodiments, the clips of the present invention are repositionable and/or retrievable. In some embodiments, at least one of the closure members includes a tissue scaffold.

摘要翻译： 本发明提供了一种未闭卵圆孔（PFO）闭合夹。 本发明的夹子包括由至少两个隔开的中央连接件连接的两个闭合件。 所述至少两个间隔开的中央连接构件中的每一个在所述关闭构件的周边上的位置处附接至每个关闭构件。 夹子被设计成使得至少两个中央连接构件延伸穿过倾斜的PFO通道，并且两个闭合构件将间隔组织的重叠层（即，隔膜和隔膜）压缩在一起以关闭PFO通道。 本发明的夹子可以由各种材料形成。 在至少一些实施例中，夹子由金属，非金属材料，生物可吸收聚合物，弹簧钢，形状记忆材料，生物可吸收形状记忆聚合物或其组合形成。 本发明的夹子部分地取决于关闭给定PFO所需的力的分布而采取各种形式。 因此，在一些实施例中，封闭构件包括弓形峰。 在其他实施例中，封闭构件包括环。 在其他实施例中，封闭构件包括尖头。 在其他实施例中，闭合构件包括用于使设备在期望的递送位置中心对中的定心元件。 在至少一些实施例中，本发明的夹子是可重新定位和/或可恢复的。 在一些实施例中，至少一个闭合构件包括组织支架。