摘要:
Devices, delivery systems, and delivery techniques for an occlusion device for closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. Specifically, an occluder with a catch member that holds the occluder in the deployed, expanded profile configuration is provided within a delivery sheath. The proximal end of the catch member includes a flap that when positioned proximal to the proximal end of the occluder holds the occluder in the expanded profile configuration. The flap is sized and formed of a material that allows the flap to deform by bending back and forth in axial and radial directions. In certain embodiments, the flap has segments divided by notches. In certain embodiments, deforming the flap in the proximal direction requires a different amount of force than deforming the flap in the distal direction.
摘要:
A closure device for sealing a percutaneous puncture in a wall of a body passageway, the closure device including at least one of a toggle configured to engage an interior surface of the body passageway or a plug configured to engage an exterior surface of the body passageway and a guide wire configured to extend from an outside of the body to inside the body passageway, wherein at least one of the toggle and the plug is associated with the guide wire.
摘要:
A device (100) for medically sealing a perivalvular leak associated with implanted valves includes a bioresorbable tissue infiltratable sheet (116) for insertion through a perivalvular leak. A filament (122) extending through the sheet (116) is also provided which when pulled causes the sheet (116) to gather around the filament (122) on either side of the perivalvular leak. The gathered position of the sheet (116) may be secured by a series of stops and/or use of a capping member (200).
摘要:
A closure device for sealing a percutaneous puncture in a wall of a body passageway, the closure device including at least one of a toggle configured to engage an interior surface of the body passageway or a plug configured to engage an exterior surface of the body passageway and a guide wire configured to extend from an outside of the body to inside the body passageway, wherein at least one of the toggle and the plug is associated with the guide wire.
摘要:
An occlusion device and method for occluding an undesirable passage through tissue, such as a septal defect, that provides an expandable cylinder or other structure that occludes the passage internally or by covering one or more openings to the passage. The occlusion device includes a wire lattice or mesh that expands from a contracted catheter-deliverable state to an expanded state that occludes the passage. The lattice or mesh has one or more layers, with layers that provide structural support to the device, and layers that provide a lattice braiding or pore sizes that promote further occlusion by a biological process, such as tissue ingrowth that further occludes the affected passage.
摘要:
A left atrial appendage occluder (100) comprises an elastic closure disc (11) connected to a fixing structure (111) which is located on one side of the closure disc. The fixing structure (111) comprises a central end portion connecting with the closure disc and a plurality of interconnected and curved struts (121), wherein at least one anchoring tip (131) is provided near the end of at least one strut (121) with the anchoring tip (131) directed toward the closure disc (11). The left atrial appendage occluder has a stable structure, a good positioning and sealing effect on the cavity wall in the left atrial appendage, and it is easy to position repeatedly. It can also be recycled before separating from a deployment device. When in surgical operation, the left atrial appendage occluder can select the position area based on the actual shape and size of the patient's left atrial appendage, so the surgical risk is lowered.
摘要:
A device for closing an opening in a tissue includes a closure body, a fastening element, and a capture strip coupleable to the closure body such that the capture strip is moveable from a first position to a second position relative to the closure body, the capture strip including a receptacle configured to receive the fastening element when the capture strip is in the first position such that movement of the capture strip from the first position to the second position causes the fastening element to urge the closure body toward the tissue.
摘要:
The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. The occluder is formed from a tube, which is cut to produce struts in each side. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and in at least some embodiments, the loops have rounded peripheries. In some embodiments, at least one of the sides includes a tissue scaffold. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is deployed so that the occluder exerts a compressive force on the septal tissue and closes the aperture.