PERFECTIONNEMENT AU PROCEDE D'ENRICHISSEMENT D'ISOMERES OPTIQUES PAR LIT MOBILE SIMULE
    1.
    发明授权
    PERFECTIONNEMENT AU PROCEDE D'ENRICHISSEMENT D'ISOMERES OPTIQUES PAR LIT MOBILE SIMULE 失效
    过程的光学异构体在模拟移动床富集

    公开(公告)号:EP1064065B2

    公开(公告)日:2006-08-16

    申请号:EP98914948.9

    申请日:1998-03-19

    申请人: Novasep S.A.

    IPC分类号: B01D15/02 C07B57/00

    摘要: The invention concerns a method for separating from a mixture two optical isomers using a simulated mobile bed, consisting of an assembly of columns (C1,C2,C3,C4, C5,C6,C7,C8) divided into at least three successive zones (I, II, III). Said method is characterised in that the amount of charge injected is greater than that of the state of a predetermined reference state, and the discharge flow is greater than that of said predetermined reference state if it is required at least to preserve the purity of the less immobilised enantiomer, or the discharge flow is less than that of the reference state if it is required to preserve the purity of the more immobilised enantiomer.

    DISPOSITIF DE PROTECTION DU LIT CHROMATOGRAPHIQUE DANS LES COLONNES CHROMATOGRAPHIQUE A COMPRESSION AXIALE DYNAMIQUE
    3.
    发明公开
    DISPOSITIF DE PROTECTION DU LIT CHROMATOGRAPHIQUE DANS LES COLONNES CHROMATOGRAPHIQUE A COMPRESSION AXIALE DYNAMIQUE 审中-公开
    DispOSITIF DE PROTECTION DU LIT CHROMATOGRAPHIQUE DANS LES COLONNES CHROMATOGRAPHIQUE A COMPRESSION AXIALE DYNAMIQUE

    公开(公告)号:EP1379867A1

    公开(公告)日:2004-01-14

    申请号:EP02761925.3

    申请日:2002-04-09

    申请人: NOVASEP

    IPC分类号: G01N30/60 B01D15/08

    摘要: The invention concerns a chromatographic device comprising: a column (12) for receiving a chromatographic bed (14) through which flows a first fluid; a piston (36) sliding inside the column (12) and exerting pressure on the bed (14), a chamber (28) containing a second fluid exerting pressure on the piston (36); a regulator (52) for the pressure exerted by the piston (36) on the bed based on the pressure inside the chamber (28), on the flow pressure of the first fluid at the intake of the column (12) and on a reference pressure on the bed (14). Said device enables to separate at least two compounds to be subjected to chromatographic analysis, while adjusting the pressure exerted on the chromatographic bed. The device efficiently uses the chromatographic bed while protecting it.

    摘要翻译: 本发明涉及一种色谱装置,其包括:用于接收色谱床(14)的柱(12),第一流体流过该色谱床; 一个在柱(12)内滑动并在床(14)上施加压力的活塞(36),一个容纳有在活塞(36)上施加压力的第二流体的腔室(28); 调节器(52),用于基于腔室(28)内的压力由柱体(12)的入口处的第一流体的流动压力以及基准 床(14)上的压力。 所述装置能够分离至少两种待进行色谱分析的化合物,同时调整施加在色谱床上的压力。 该设备有效地使用色谱床,同时保护它。

    PERFECTIONNEMENT AU PROCEDE D'ENRICHISSEMENT D'ISOMERES OPTIQUES PAR LIT MOBILE SIMULE
    4.
    发明公开
    PERFECTIONNEMENT AU PROCEDE D'ENRICHISSEMENT D'ISOMERES OPTIQUES PAR LIT MOBILE SIMULE 失效
    过程的光学异构体在模拟移动床富集

    公开(公告)号:EP1064065A1

    公开(公告)日:2001-01-03

    申请号:EP98914948.9

    申请日:1998-03-19

    申请人: Novasep S.A.

    IPC分类号: B01D15/02 C07B57/00

    摘要: The invention concerns a method for separating from a mixture two optical isomers using a simulated mobile bed, consisting of an assembly of columns (C1,C2,C3,C4, C5,C6,C7,C8) divided into at least three successive zones (I, II, III). Said method is characterised in that the amount of charge injected is greater than that of the state of a predetermined reference state, and the discharge flow is greater than that of said predetermined reference state if it is required at least to preserve the purity of the less immobilised enantiomer, or the discharge flow is less than that of the reference state if it is required to preserve the purity of the more immobilised enantiomer.