-
公开(公告)号：EP2276548B1
公开(公告)日：2013-03-27
申请号：EP09728317.0
申请日：2009-04-03
申请人： Novasep
CPC分类号： B01D15/1864
-
2.发明公开
公开(公告)号：EP1128881A1
公开(公告)日：2001-09-05
申请号：EP99950884.9
申请日：1999-10-29
IPC分类号： B01D15/02
CPC分类号： B01D15/1828 , B01D2215/023
摘要： The invention concerns a method for separating at least a constituent of a mixture in a set of looping chromatographic columns, the loop comprising at least a point for injecting a load, a point for drawing off the raffinate, a point for injecting an eluting agent and a point for drawing of the extract. The method consists in: determining between an injection point and a drawing off point or vice-versa a chromatographic zone and at the end of a specific time interval, the whole set of injection points and drawing off points are offset by the same number of columns or column sections and advantageously from one column or one column section in a specific direction defined with respect to that of the flow of the main fluid circulating through the loop. During said time interval, the offsetting of the different injection and drawing off points of at least one column or column section is carried out at different times such that the length of the zones defined by the different points varies. The invention is useful in particular for separating stereoisomers for pharmaceutical purposes.
-
公开(公告)号：EP2276548A1
公开(公告)日：2011-01-26
申请号：EP09728317.0
申请日：2009-04-03
申请人： Novasep
CPC分类号： B01D15/1864
摘要： The invention relates to a method of separating fractions of a mixture to be separated, comprising the following step: provision of a device comprising at least two chromatography columns connected in series; discontinuous injection of the mixture to be separated, at a single point in the device; discontinuous withdrawal of the fraction enriched with the product of interest, at a single point in the device; and injection of eluants into each column and displacement of the eluant injection points, the eluants having different eluting strengths. The method allows effective and easily implementable separation.
摘要翻译： 本发明涉及一种分离待分离混合物馏分的方法，包括以下步骤：提供包含至少两个串联连接的色谱柱的装置; 在装置中的单个点不连续地注入待分离的混合物; 在装置中的单个点不连续地抽出富含目的产物的部分; 并向每个柱中注入洗脱液并移出洗脱液注射点，洗脱液具有不同的洗脱强度。 该方法允许有效且容易实施的分离。
-
4.发明授权PROCEDE ET DISPOSITIF DE CHROMATOGRAPHIE INTEGRANT UNE ETAPE DE CONCENTRATION 有权色谱方法和设备WHAT浓缩步骤INTEGRATE
公开(公告)号：EP1558355B1
公开(公告)日：2006-04-19
申请号：EP03767859.6
申请日：2003-10-29
申请人： Novasep
IPC分类号： B01D15/02
CPC分类号： B01D15/1828 , B01D15/24
摘要： The invention concerns a method for multiple-column chromatographic separation producing at least two fractions, comprising the following steps: in output of the extract, zone I, or the raffinate zone, zone III: (i) drawing at least part of the output flow of said zone; (ii) concentrating said part; and (iii) re-injecting at least partly said concentrated part. The invention also concerns a device for implementing said method.
-
5.发明公开PROCEDE ET DISPOSITIF DE CHROMATOGRAPHIE INTEGRANT UNE ETAPE DE CONCENTRATION 有权色谱方法和设备WHAT浓缩步骤INTEGRATE
公开(公告)号：EP1558355A2
公开(公告)日：2005-08-03
申请号：EP03767859.6
申请日：2003-10-29
申请人： NOVASEP
IPC分类号： B01D15/02
CPC分类号： B01D15/1828 , B01D15/24
摘要： The invention concerns a method for multiple-column chromatographic separation producing at least two fractions, comprising the following steps: in output of the extract, zone I, or the raffinate zone, zone III: (i) drawing at least part of the output flow of said zone; (ii) concentrating said part; and (iii) re-injecting at least partly said concentrated part. The invention also concerns a device for implementing said method.
-
公开(公告)号：EP1128881B1
公开(公告)日：2005-06-08
申请号：EP99950884.9
申请日：1999-10-29
IPC分类号： B01D15/02
CPC分类号： B01D15/1828 , B01D2215/023
摘要： The invention concerns a method for separating at least a constituent of a mixture in a set of looping chromatographic columns, the loop comprising at least a point for injecting a load, a point for drawing off the raffinate, a point for injecting an eluting agent and a point for drawing of the extract. The method consists in: determining between an injection point and a drawing off point or vice-versa a chromatographic zone and at the end of a specific time interval, the whole set of injection points and drawing off points are offset by the same number of columns or column sections and advantageously from one column or one column section in a specific direction defined with respect to that of the flow of the main fluid circulating through the loop. During said time interval, the offsetting of the different injection and drawing off points of at least one column or column section is carried out at different times such that the length of the zones defined by the different points varies. The invention is useful in particular for separating stereoisomers for pharmaceutical purposes.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.01 秒)
