PROCESS
    1.
    发明公开
    PROCESS 审中-公开
    处理

    公开(公告)号:EP2283037A1

    公开(公告)日:2011-02-16

    申请号:EP09749882.8

    申请日:2009-05-20

    申请人: Novo Nordisk A/S

    IPC分类号: C07K14/685 C07K1/107

    摘要: A process for performing a ring closure on a fully protected peptide to form a protected cyclic peptide comprising the steps of: i) selectively deprotecting the connectable portions of the ring to be closed; ii) connecting the deprotected connectable portions of step i) to form the protected cyclic peptide.

    摘要翻译: 一种对完全保护的肽进行闭环以形成受保护的环状肽的方法,其包括以下步骤:i)选择性地将待闭合环的可连接部分脱保护; ii)连接步骤i)的脱保护的可连接部分以形成受保护的环状肽。