-
公开(公告)号:EP2283037A1
公开(公告)日:2011-02-16
申请号:EP09749882.8
申请日:2009-05-20
申请人: Novo Nordisk A/S
IPC分类号: C07K14/685 , C07K1/107
CPC分类号: C07K14/685 , A61K38/00 , C07K1/061 , C07K1/107
摘要: A process for performing a ring closure on a fully protected peptide to form a protected cyclic peptide comprising the steps of: i) selectively deprotecting the connectable portions of the ring to be closed; ii) connecting the deprotected connectable portions of step i) to form the protected cyclic peptide.
摘要翻译: 一种对完全保护的肽进行闭环以形成受保护的环状肽的方法,其包括以下步骤:i)选择性地将待闭合环的可连接部分脱保护; ii)连接步骤i)的脱保护的可连接部分以形成受保护的环状肽。
-
公开(公告)号:EP0687298A1
公开(公告)日:1995-12-20
申请号:EP94908993.0
申请日:1994-03-04
申请人: NOVO NORDISK A/S
发明人: KOFOD, Lene Venke , DALBOGE, Henrik , ANDERSEN, Lene Nonboe , KAUPPINEN, Markus Sakari , CHRISTGAU, Stephan , HELDT-HANSEN, Hans Peter , CHRISTOPHERSEN, Claus , NIELSEN, Per Munk , VORAGEN, Alphons Gerard Joseph , SCHOLS, Hendrik Arie
CPC分类号: C13B10/083 , A23K20/189 , A23L2/84 , A23L29/06 , C12N9/2402 , C12Y302/01171 , C13K13/00
摘要: An enzyme exhibiting rhamnogalacturonase activity, which enzyme: a) is encoded by the DNA sequence shown in SEQ ID No. 1 or a sequence homologous thereto encoding a polypeptide with RGase activity, b) has the amino acid sequence shown in SEQ ID No. 2 or an analogue thereof, c) is reactive with an antibody raised against the enzyme encoded by the DNA sequence shown in SEQ ID No. 1, d) has a pH optimum above pH 5, and/or e) has a relative activity of at least 30% at a pH in the range of 5.5-6.5. The enzyme may be used for reducing the viscosity of a plant cell wall material and for extracting high molecular weight molecules from a plant cell wall material.
摘要翻译: 显示鼠李糖半乳糖醛酸酶活性的酶,其中酶:a)由SEQ ID No.1所示的DNA序列或与其同源的编码具有RGase活性的多肽的序列编码,b)具有SEQ ID No.2所示的氨基酸序列 c)与针对由SEQ ID No.1所示的DNA序列编码的酶产生的抗体反应,d)具有高于pH 5的最佳pH,和/或e)具有以下的相对活性: 在5.5-6.5范围内的pH下至少30%。 该酶可用于降低植物细胞壁材料的粘度并从植物细胞壁材料中提取高分子量分子。
-
公开(公告)号:EP0941359A1
公开(公告)日:1999-09-15
申请号:EP97912081.0
申请日:1997-11-21
申请人: NOVO NORDISK A/S
IPC分类号: C12P19
CPC分类号: C12P19/14
摘要: The invention relates to a method for liquefying starch, wherein a starch substrate is treated in aqueous medium with a carbohydrate-binding domain (CBD) and at least one amylolytic enzyme.
-
-