A FLEXIBLE PISTON ROD
    1.
    发明授权
    A FLEXIBLE PISTON ROD 有权
    柔性杆

    公开(公告)号:EP1267963B1

    公开(公告)日:2005-06-01

    申请号:EP01915108.3

    申请日:2001-03-16

    申请人: NOVO NORDISK A/S

    IPC分类号: A61M5/315 A61M5/145

    摘要: A flexible piston rod for an injection device, which piston has the form of a helical spring made up from a number of narrowly adjacent turns of windings. These turns provide an external thread, which thread fits into the internal thread of a nut element. When the nut element is rotated the piston rod is advanced forward, which movement is used to displace a piston inside a cartridge containing a fluid to be expelled. In order to prevent the piston rod from rotating when the nut element is rotated, the helical spring making up the piston rod is provided with a longitudinal spine, which is located at a peripheral area of the helical spring. The spine can either be a mechanical removal of a part of the out-turned area of each winding, or it can be a reduction or removal of an initial tension in a longitudinal area of the helical spring.

    DOSE SETTING DEVICE
    2.
    发明授权

    公开(公告)号:EP0910419B1

    公开(公告)日:2004-05-26

    申请号:EP97928121.9

    申请日:1997-06-09

    申请人: NOVO NORDISK A/S

    IPC分类号: A61M5/31

    摘要: The present invention relates to a drug delivery device wherein a dose to be apportioned from a cartridge is set by changing the relative position of co-operating dose setting elements (3, 5) and is injected by pressing a button (5) until this button abuts a stop (6). By operation of count up (7) or count down (8) buttons the dose is set and read into an electronic circuit (9) comprising a microprocessor and the dose setting movement of the dose setting elements relative to each other is performed by a motor (11) controlled by the circuit in accordance with the read in dose. The set dose is shown on a display (10). The motor (11) is further controlled to perform certain movements of the piston rod (3) so as retraction of this rod when a cartridge (1) is going to be changed an advancing of the piston rod to abutment with the piston (2) after the cartridge has been changed and further to advance this piston to expel air from the cartridge.

    A DISPLACEMENT DEVICE FOR CONTROLLED DISPENSING OF A DOSE OF A LIQUID CONTAINED IN A CARTRIDGE
    3.
    发明授权
    A DISPLACEMENT DEVICE FOR CONTROLLED DISPENSING OF A DOSE OF A LIQUID CONTAINED IN A CARTRIDGE 失效
    其它方向之前,液体的剂量受控的给药包含在一个盒

    公开(公告)号:EP0988075B1

    公开(公告)日:2003-12-17

    申请号:EP98925454.5

    申请日:1998-06-08

    申请人: NOVO NORDISK A/S

    IPC分类号: A61M5/315 A61M5/20

    摘要: The present invention relates to an improved displacement device (1) for controlled dispensing of a dose of a liquid contained in a cartridge (40), said displacement device (1) comprising a housing (5) incorporating: a means (6) for accommodating said cartridge (40), a manually activatable displaceable elongated dose dispensing means (20), said elongated dose dispensing means (20) having a first end part (22) extending to the exterior of the housing (5), an elongated piston rod (30) connected with a displaceable piston (32), said piston (32) being adapted to press out the liquid contained in said cartridge (40), and said elongated piston rod (30) having a plurality of transversely extending teeth (25) arranged along its length, a toothed displacing means (14), a user-operated dose setting means (8, 10, 12), said user-operated dose setting means (8, 10, 12) and said toothed displacing means (14) being operatively connected to cause movement of said toothed displacing means (14) in response to the operation of the dose setting means (8, 10, 12), pinion means (35) having a shaft (37), said pinion means (35) being rotatably secured to said elongated dose dispensing means (20), said pinion means (35) being arranged to engage the teeth of said toothed displacing means (14) and the teeth (25) of the piston rod (30).

    DISPLACEMENT SYSTEM FOR CONTROLLED INFUSION OF A LIQUID
    5.
    发明公开
    DISPLACEMENT SYSTEM FOR CONTROLLED INFUSION OF A LIQUID 失效
    资助体系的液体控输注

    公开(公告)号:EP0721358A1

    公开(公告)日:1996-07-17

    申请号:EP94928305.0

    申请日:1994-09-27

    申请人: NOVO NORDISK A/S

    IPC分类号: A61M5

    CPC分类号: A61M5/14566

    摘要: In a displacement system for controlled infusion of a liquid from a cartridge comprising a tubular vessel (1), which is at a rear end closed by a piston (3) which may be forced by a piston rod (8) moving into the vessel (1) in the axial direction thereof to press out the liquid through an outlet (2) arranged at a front end of the vessel (1), the piston rod (8) is provided as a flexible incompressible construction which is by a piston rod guide (9) behind the rear end of the cartridge deflected away from the axis of this cartridge, preferably 180°. The piston rod guide (9) has a guiding track comprising a curved part and linear parts at each end of the curved part ensuring that the piston rod is guided along a length (a) in the direction of the axis of the cartridge which length (a) is longer than the distance (b) between the two axes of the piston rod parts projecting from the piston rod guide. The guiding track is further elaborated to the very shape which the curved part of the piston rod will spontaneously adopt when its end portions are kept parallel.

    A DISPLACEMENT DEVICE FOR CONTROLLED DISPENSING OF A DOSE OF A LIQUID CONTAINED IN A CARTRIDGE
    9.
    发明公开
    A DISPLACEMENT DEVICE FOR CONTROLLED DISPENSING OF A DOSE OF A LIQUID CONTAINED IN A CARTRIDGE 失效
    以前不同方向的液体的剂量受控的给药包含在一个盒

    公开(公告)号:EP0988075A1

    公开(公告)日:2000-03-29

    申请号:EP98925454.5

    申请日:1998-06-08

    申请人: NOVO NORDISK A/S

    IPC分类号: A61M5/315 A61M5/20

    摘要: The present invention relates to an improved displacement device (1) for controlled dispensing of a dose of a liquid contained in a cartridge (40), said displacement device (1) comprising a housing (5) incorporating: a means (6) for accommodating said cartridge (40), a manually activatable displaceable elongated dose dispensing means (20), said elongated dose dispensing means (20) having a first end part (22) extending to the exterior of the housing (5), an elongated piston rod (30) connected with a displaceable piston (32), said piston (32) being adapted to press out the liquid contained in said cartridge (40), and said elongated piston rod (30) having a plurality of transversely extending teeth (25) arranged along its length, a toothed displacing means (14), a user-operated dose setting means (8, 10, 12), said user-operated dose setting means (8, 10, 12) and said toothed displacing means (14) being operatively connected to cause movement of said toothed displacing means (14) in response to the operation of the dose setting means (8, 10, 12), pinion means (35) having a shaft (37), said pinion means (35) being rotatably secured to said elongated dose dispensing means (20), said pinion means (35) being arranged to engage the teeth of said toothed displacing means (14) and the teeth (25) of the piston rod (30).

    SOLID DOSE DELIVERY DEVICE
    10.
    发明公开
    SOLID DOSE DELIVERY DEVICE 审中-公开
    装置给药固体剂量

    公开(公告)号:EP2411082A1

    公开(公告)日:2012-02-01

    申请号:EP10710355.8

    申请日:2010-03-26

    申请人: Novo Nordisk A/S

    IPC分类号: A61M37/00

    CPC分类号: A61M37/0069

    摘要: The invention relates to a medicament delivery device (1, 100) for delivering one or more solid dose pegs (10, 110) through the skin. The device (1, 100) has a number of exit openings (9, 109) corresponding to the number of solid dose pegs (10, 110) to be delivered. A detachable portion (3, 103) of the device (1, 100) is removed before use to uncover the exit openings (9, 109) and a release rod (17, 117). When the exit openings (9, 109) are pressed against the skin the release rod (17, 117) automatically disables a safety mechanism adapted to prevent unintended activation of the device (1, 100).