公开(公告)号：EP1432464B1

公开(公告)日：2009-01-14

申请号：EP02799393.0

申请日：2002-09-23

申请人： NOVO NORDISK A/S

发明人： POULSEN, Jens, Ulrik ,  KRAG-JENSEN, Christian

IPC分类号： A61M5/168

CPC分类号： A61M5/14248 ,  A61M5/1413 ,  A61M5/14244 ,  A61M5/16827 ,  A61M2005/14208 ,  A61M2005/14268 ,  A61M2005/1581 ,  G06F19/00

摘要： The invention relates to a modular drug delivery system, comprising a reservoir unit and a control unit in combination with at least one further reservoir or control unit, whereby each combination of a reservoir unit and a control provides different capabilities. More specifically,the present invention provides a system for delivering a drug to a user, comprising a reservoir unit, a control unit, and at least one further reservoir unit or control unit, wherein each reservoir unit is adapted to receive at least one command from a control unit and perform an action in response thereto, and comprises a reservoir adapted to contain a liquid drug and includes, in a situation of use, associated outlet means. The system further comprises expelling means for expelling a drug out of the reservoir through the outlet means. Each control unit comprises control means providing one or more commands for controlling the operation of a reservoir unit, wherein each combination of a reservoir unit and a control unit is adapted to provide a system with different capabilities

公开(公告)号：EP1276529B1

公开(公告)日：2006-06-21

申请号：EP01921255.4

申请日：2001-04-11

申请人： NOVO NORDISK A/S

发明人： LJUNGGREEN, Henrik ,  POULSEN, Jens, Ulrik ,  AASMUL, Søren ,  CHRISTENSEN, Lars, Hofmann ,  MØLLER-JENSEN, Jens ,  MØLLER-JENSEN, Peter

IPC分类号： A61M5/315

CPC分类号： A61M5/31511 ,  A61M5/31501 ,  A61M5/31543 ,  A61M5/3156 ,  A61M5/31585 ,  A61M5/31593 ,  A61M2005/31518 ,  A61M2005/31588

摘要： A drug delivery device comprising a housing (1) with a drug container (2) being provided with delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2). The housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2) and rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism. The one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.

公开(公告)号：EP1171076B1

公开(公告)日：2005-08-10

申请号：EP00916824.6

申请日：2000-04-12

申请人： NOVO NORDISK A/S

发明人： BUCH-RASMUSSEN, Thomas ,  AASMUL, Soren ,  FLINK, James, M. ,  HANSEN, Philip ,  JUUL-MORTENSEN, Claus ,  POULSEN, Jens, Ulrik

IPC分类号： A61J1/00 ,  A61M5/30

CPC分类号： A61M37/0069 ,  A61M31/007 ,  A61M2205/123

摘要： A cassette for storing and insertion of a solid medicine peg appears as a unit having a first bore (2) which accommodates the medicine peg (3) and has a diameter corresponding to the diameter of this peg (3), a second bore (4) in coaxial extension of the first bore (2) and having a diameter larger than the diameter of the first bore (2), an inserter having a shaft (5) fitting into the first bore (2) and a guiding head (6) in coaxial extension of the shaft (5) fitting into the second bore. The inserter shaft (5) has one end adjacent to the peg (3) and the other connected to the guiding head (6) which projects from the cassette. The head (6) fits into the second bore with a fitting providing a diffusion tight sealing and the distal end of the unit is closed by a membrane diffusion tightly sealing this distal end.

公开(公告)号：EP1501405A1

公开(公告)日：2005-02-02

申请号：EP03717172.5

申请日：2003-04-29

申请人： NOVO NORDISK A/S

发明人： CHRISTENSEN, Lars, Hofmann ,  POULSEN, Jens, Ulrik ,  SIMONSEN, Jan, H.

IPC分类号： A61B5/00

CPC分类号： A61B5/6887 ,  A61B5/0402 ,  A61B5/14532

摘要： This invention relates to a doser comprising a syringe (2) with a needle (3) which extends beyond the doser (1), which comprises an engagement face (4) in the vicinity of the needle so that the engagement face rests against the surface of the tissue into which the needle is inserted. Detector means (5) are provided on said engagement face to sample signals on the skin of the patient, said means being arranged for providing heart rate signals. The invention further provides means (13) for receiving information related to health monitoring of a patient. This provides a doser that may record heart rate, EKG, BGM and hypo-alarm administered medicine. The doser may further be arranged to calculate an appropriate dose of medication on the basis of a number of acquired inputs.

公开(公告)号：EP0973567B1

公开(公告)日：2003-04-02

申请号：EP97949987.8

申请日：1997-12-11

申请人： NOVO NORDISK A/S

发明人： POULSEN, Jens, Ulrik

IPC分类号： A61M5/30

CPC分类号： A61M5/30 ,  A61M5/2046 ,  A61M5/24 ,  A61M5/31525 ,  A61M5/31551 ,  A61M5/31591

摘要： An injector comprising a changeable cylinder ampoule (2) containing medicine for a number of injections into which ampoule a piston (4) is pressed by a piston rod (9) driven by a drive mechanism to dispense a dose of medicine through a nozzle (5) as a high speed jet which penetrates the skin. The injector comprises a distal part (1) accommodating the cylinder ampoule (2) and a proximal part (8) containing the drive mechanism and the piston rod (9) which can be advanced a set distance by the drive mechanism when released, the distal and the proximal parts being provided with mutually engaging threads so that one of these parts can successively be screwed into the other to set a dose to be delivered by the device.

公开(公告)号：EP1144028A1

公开(公告)日：2001-10-17

申请号：EP99957259.7

申请日：1999-11-30

申请人： NOVO NORDISK A/S

发明人： AASMUL, Soren ,  POULSEN, Jens, Ulrik ,  CHRISTENSEN, Lars, Hofmann

IPC分类号： A61M5/00 ,  A61B5/00 ,  G06F19/00 ,  G11C11/00

CPC分类号： G06Q50/24 ,  A61B5/0002 ,  A61B5/14532 ,  A61B2560/0406 ,  A61B2560/0443 ,  A61B2562/0219 ,  A61M5/003 ,  A61M5/24 ,  A61M2205/505 ,  A61M2205/52 ,  G06F19/00 ,  G06F19/325 ,  G06F19/3468 ,  G06F19/3475 ,  G06F19/3481 ,  G16H10/60 ,  G16H50/50 ,  Y10S128/92 ,  Y10S128/921

摘要： The invention relates to a method and apparatus for calculating a plurality of options (305) for bringing a user into and/or keeping a user substantially in compliance with a medical regime of a medical self treatment, with the steps of: collecting, in a user individual database, data representing values (302,306) of a group of parameters relating to the user's physiological condition, estimating one or more future values for a specific parameter (301) from the group of the parameters on the basis of information in the user individual database, and automatically calculating a plurality of options (305) on the basis of the estimated one or more future values and the data in the user individual database, so as to provide for two or more options and at least one related value for each option, each option and related value bringing a value of the specific parameter within a range of acceptable values at a given future point in time.

公开(公告)号：EP1135056B1

公开(公告)日：2006-08-16

申请号：EP99972900.7

申请日：1999-11-30

申请人： NOVO NORDISK A/S

发明人： SIMONSEN, Jan, Henning ,  POULSEN, Jens, Ulrik ,  ROKKJAER, Kent, Halfdan ,  CHRISTENSEN, Lars, Hofmann ,  AASMUL, Soren ,  LAV, Steffen

IPC分类号： A61B5/00 ,  G06F19/00

CPC分类号： G06F19/3468 ,  A61B5/0002 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150267 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/15113 ,  A61B5/157 ,  A61B5/7264 ,  A61B2560/0406 ,  A61B2560/0443 ,  A61B2562/0219 ,  A61M5/003 ,  A61M5/24 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/505 ,  A61M2205/52 ,  G06F19/00 ,  G06F19/325 ,  G06F19/3418 ,  G06F19/3475 ,  G06F19/3481 ,  G06Q50/24 ,  G16H10/60 ,  G16H50/50 ,  Y10S128/92 ,  Y10S128/921

摘要： This invention relates to a system for self treatment. The system consists of several portable modules where one of the modules is designated as a master module. The master module controls, supervises and monitors all the mutual information and data exchange between itself and the rest of the modules. The modules can e.g. consist of a BGM, a doser, an inhaler, a tablet dispenser and a storage container. The modules may be able to generate and store data which is transmitted to the master module if it is within range and active. If the master module is not within range, the data is kept locally in the module until the master module is available or a new master module is designated. The master module or another specific module can send the data to an external unit like a computer or database for further processing. A physician or an expert care-team can access the data in the database and give guidance to the patient on the basis of these processed data. This processing could also be done automatically by utilization of an expert system.

摘要翻译： 本发明涉及一种用于治疗自身的系统。 的几个便携式模块中的系统besteht其中模块中的一个被指定为主模块。 主模块的控制，监督和监控所有的互信息与本身和模块的其余部分之间的数据交换。 该模块可以例如 由一个BGM，在吸入器加料器，一个药片分配器和存储容器的。 这些模块可以是能够产生和存储数据的所有其是反式mitted到主模块，如果它是在范围内和活性。 如果主模块不在范围内时，数据被本地模块中，直到主模块可用或新的主模块被指定保存。 主模块或另一个具体的模块可以将数据发送到外部单元等用于进一步处理的计算机或数据库。 医生或专家护理团队可以访问数据库中的数据，并合成处理的数据的基础上，对患者给予指导。 这种处理因此可以由专家系统的利用率自动完成。

公开(公告)号：EP0927055B1

公开(公告)日：2001-12-05

申请号：EP97918919.8

申请日：1997-09-16

申请人： NOVO NORDISK A/S

发明人： BUCH-RASMUSSEN, Thomas ,  POULSEN, Jens, Ulrik ,  LJUNGGREEN, Henrik ,  JENSEN, Jens, Moller

IPC分类号： A61M5/178 ,  A61M5/31

CPC分类号： A61M5/31525 ,  A61M5/204 ,  A61M5/31555 ,  A61M5/31561 ,  A61M5/3158 ,  A61M5/31595

公开(公告)号：EP1135056A1

公开(公告)日：2001-09-26

申请号：EP99972900.7

申请日：1999-11-30

申请人： Novo Nordisk A/S

发明人： SIMONSEN, Jan, Henning ,  POULSEN, Jens, Ulrik ,  ROKKJAER, Kent, Halfdan ,  CHRISTENSEN, Lars, Hofmann ,  AASMUL, Soren ,  LAV, Steffen

IPC分类号： A61B5/00 ,  G06F19/00

CPC分类号： G06F19/3468 ,  A61B5/0002 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150267 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/15113 ,  A61B5/157 ,  A61B5/7264 ,  A61B2560/0406 ,  A61B2560/0443 ,  A61B2562/0219 ,  A61M5/003 ,  A61M5/24 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/505 ,  A61M2205/52 ,  G06F19/00 ,  G06F19/325 ,  G06F19/3418 ,  G06F19/3475 ,  G06F19/3481 ,  G06Q50/24 ,  G16H10/60 ,  G16H50/50 ,  Y10S128/92 ,  Y10S128/921

摘要： This invention relates to a system for self treatment. The system consists of several portable modules where one of the modules is designated as a master module. The master module controls, supervises and monitors all the mutual information and data exchange between itself and the rest of the modules. The modules can e.g. consist of a BGM, a doser, an inhaler, a tablet dispenser and a storage container. The modules may be able to generate and store data which is transmitted to the master module if it is within range and active. If the master module is not within range, the data is kept locally in the module until the master module is available or a new master module is designated. The master module or another specific module can send the data to an external unit like a computer or database for further processing. A physician or an expert care-team can access the data in the database and give guidance to the patient on the basis of these processed data. This processing could also be done automatically by utilization of an expert system.

公开(公告)号：EP0959922A1

公开(公告)日：1999-12-01

申请号：EP97906803.0

申请日：1997-02-20

申请人： NOVO NORDISK A/S

发明人： JENSEN, Jens, Moller ,  POULSEN, Jens, Ulrik ,  SMEDEGAARD, Jorgen, K.

IPC分类号： A61M5

CPC分类号： A61M5/31568 ,  A61M5/31525 ,  A61M5/31533 ,  A61M5/31535 ,  A61M5/31556 ,  A61M5/31566 ,  A61M5/31573 ,  A61M2005/3125 ,  A61M2005/3126 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/583

摘要： A syringe having a dose setting mechanism, a button which can be operated to inject a set dose, a switch operated at a time between the start and the completion of the injection and an electronic representation of parameters such as magnitudes of the set dose and the latest injected dose, which syringe further has a stop watch which is reset and started when the switch is operated. The status of the watch function is electronically represented and is together with the electronic represented parameters reproduced in a display showing the number of hours passed since the operation of the switch by switching on a corresponding number of 30° segments of a circle. Dose sizes are shown by common Arabic numerals.