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公开(公告)号：EP1292324A2
公开(公告)日：2003-03-19
申请号：EP01927641.9
申请日：2001-04-30
CPC分类号： A61K38/28
摘要： This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.
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公开(公告)号：EP1487518B1
公开(公告)日：2010-02-17
申请号：EP03711717.3
申请日：2003-03-24
发明人： VAN DEN BERGHE, Greta , BERCKMANS, Daniel , AERTS, Jean-Marie , DE MOOR, Bart , PLUYMERS, Bert , DE SMET, Frank , VAN HERPE, Tom
CPC分类号： A61M5/142 , A61M5/1723 , A61M2005/14208 , A61M2205/6018 , A61M2230/201 , G06F19/00
摘要： A control system is described for use with a system configured to maintain normoglycemia in a subject under a condition of insulin resistance or under a condition of increased glucose turnover, the system having a sensor to measure glycemia level in a subject and a programmable actuator to delivery a blood glucose regulator to said subject, wherein the control system is configurable to adapt the administration levels of the blood glucose regulator to a desired glycemia level in said subject, the control system comprising an adaptive model; - wherein the adaptive model is configurable so that in the initial phase it is based on the factors patient profile and on-admission parameters that determine an initial model and in a later phase on factors that influence the dynamic behaviour of the patient.
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公开(公告)号：EP1487518A1
公开(公告)日：2004-12-22
申请号：EP03711717.3
申请日：2003-03-24
发明人： VAN DEN BERGHE, Greta , BERCKMANS, Daniel , AERTS, Jean-Marie , DE MOOR, Bart , PLUYMERS, Bert , DE SMET, Frank
CPC分类号： A61M5/142 , A61M5/1723 , A61M2005/14208 , A61M2205/6018 , A61M2230/201 , G06F19/00
摘要： A control system is described for use with a system configured to maintain normoglycemia in a subject under a condition of insulin resistance or under a condition of increased glucose turnover, the system having a sensor to measure glycemia level in a subject and a programmable actuator to delivery a blood glucose regulator to said subject, wherein the control system is configurable to adapt the administration levels of the blood glucose regulator to a desired glycemia level in said subject, the control system comprising an adaptive model; - wherein the adaptive model is configurable so that in the initial phase it is based on the factors patient profile and on-admission parameters that determine an initial model and in a later phase on factors that influence the dynamic behaviour of the patient.
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