COMPOSITIONS AND METHODS FOR TARGETED NUCLEIC ACID SEQUENCE ENRICHMENT AND HIGH EFFICIENCY LIBRARY GENERATION
    2.
    发明公开
    COMPOSITIONS AND METHODS FOR TARGETED NUCLEIC ACID SEQUENCE ENRICHMENT AND HIGH EFFICIENCY LIBRARY GENERATION 审中-公开
    组合物和有针对性的核序列富集方法及节能图书馆的生产

    公开(公告)号:EP2807292A4

    公开(公告)日:2015-08-26

    申请号:EP13740653

    申请日:2013-01-25

    IPC分类号: C40B50/06 C12N15/10

    摘要: The present invention provides methods, compositions and kits for targeted nucleic acid sequence enrichment in a nucleic acid sample and for high efficiency nucleic acid library generation for next generation sequencing (NGS). Specifically, the methods, compositions and kits provided herein are useful for the production and capture of amplification-ready, target-specific and strand-specific regions of interest from nucleic acid samples containing complex DNA.

    摘要翻译: 本发明提供了方法,组合物和用于靶向的核酸序列的试剂盒富集的核酸样品中,对于高效率的核酸文库产生用于下一代测序(NGS)。 具体地,方法,组合物和在提供试剂盒可用于从含有复杂的DNA的核酸样品扩增感兴趣就绪,靶特异性和海滩区域的生产和捕获是有用的。