公开(公告)号：EP1785492B1

公开(公告)日：2010-05-26

申请号：EP06022844.2

申请日：1997-06-06

申请人： Nagase ChemteX Corporation ,  Suntory Holdings Limited ,  NAGASE & COMPANY, LTD.

发明人： Tanaka, Satohiro ,  Yaguchi, Toshiaki ,  Shimizu, Sakayu ,  Sogo, Tsutomu ,  Fujikawa, Shigeaki

IPC分类号： C12Q1/68

CPC分类号： C12P7/6427 ,  A23D9/007 ,  A23K20/158 ,  A23L33/12 ,  C11C1/045 ,  C12P7/6472 ,  C12R1/645 ,  C12R1/89

公开(公告)号：EP2213750A1

公开(公告)日：2010-08-04

申请号：EP10160357.9

申请日：1997-06-06

申请人： Nagase ChemteX Corporation ,  Suntory Holdings Limited ,  Nagase & Co., Ltd.

发明人： Tanaka, Satohiro ,  Yaguchi, Toshiaki ,  Shimizu, Sakayu ,  Sogo, Tsutomu ,  Fujikawa, Shigeaki

IPC分类号： C12Q1/68

CPC分类号： C12P7/6427 ,  A23D9/007 ,  A23K20/158 ,  A23L33/12 ,  C11C1/045 ,  C12P7/6472 ,  C12R1/645 ,  C12R1/89

摘要： There is provided a process for preparing lipids containing docosahexaenoic acid and/or docosapentaenoic acid, comprising: cultivating in a medium a microorganism of genus Ulkenia having the ability to produce lipids containing docosahexaenoic acid and/or docosapentaenoic acid, and recovering said lipids from a culture; wherein globose or oval cells and biflagellate zoospores are observed when the microorganism is cultured in a KMV liquid medium at 20°C in the dark, whereas a network of ectoplasm filaments is not observed.

摘要翻译： 提供了一种用于制备含有二十二碳六烯酸和/或二十二碳五烯酸的脂质的方法，包括：在培养基中培养具有产生含有二十二碳六烯酸和/或二十二碳五烯酸的脂质的能力的乌尔肯尼氏菌属微生物，并从培养物中回收所述脂质 ; 当在黑暗中在20℃下在KMV液体培养基中培养微生物时观察到球状或椭圆形细胞和双歧杆菌游动孢子，而没有观察到外质丝网络。

公开(公告)号：EP1785492A3

公开(公告)日：2007-06-27

申请号：EP06022844.2

申请日：1997-06-06

申请人： Nagase ChemteX Corporation ,  SUNTORY LIMITED ,  NAGASE & COMPANY, LTD.

发明人： Tanaka, Satohiro ,  Yaguchi, Toshiaki ,  Shimizu, Sakayu ,  Sogo, Tsutomu ,  Fujikawa, Shigeaki

IPC分类号： C12Q1/68

CPC分类号： C12P7/6427 ,  A23D9/007 ,  A23K20/158 ,  A23L33/12 ,  C11C1/045 ,  C12P7/6472 ,  C12R1/645 ,  C12R1/89

摘要： A process for preparing lipids which contain docosahexaenoic acid (DHA) and/ or docosapentaenoic acid (DPA) is disclosed. The process includes the steps of cultivating in a medium a microorganism of genus Ulkenia having the ability to produce lipids containing docosahexaenoic acid and/or docosapentaenoic acid, and recovering said lipids from a culture. The process may further comprise the step of separating the docosahexaenoic acid and/ or docosapentaenoic acid from the lipids.

公开(公告)号：EP1785492A2

公开(公告)日：2007-05-16

申请号：EP06022844.2

申请日：1997-06-06

申请人： Nagase ChemteX Corporation ,  SUNTORY LIMITED ,  NAGASE & COMPANY, LTD.

发明人： Tanaka, Satohiro ,  Yaguchi, Toshiaki ,  Shimizu, Sakayu ,  Sogo, Tsutomu ,  Fujikawa, Shigeaki

IPC分类号： C12Q1/68

CPC分类号： C12P7/6427 ,  A23D9/007 ,  A23K20/158 ,  A23L33/12 ,  C11C1/045 ,  C12P7/6472 ,  C12R1/645 ,  C12R1/89

摘要： A process for preparing lipids which contain docosahexaenoic acid (DHA) and/ or docosapentaenoic acid (DPA) is disclosed. The process includes the steps of cultivating in a medium a microorganism of genus Ulkenia having the ability to produce lipids containing docosahexaenoic acid and/or docosapentaenoic acid, and recovering said lipids from a culture. The process may further comprise the step of separating the docosahexaenoic acid and/ or docosapentaenoic acid from the lipids.

摘要翻译： 公开了一种制备含有二十二碳六烯酸（DHA）和/或二十二碳五烯酸（DPA）的脂质的方法。 该方法包括在培养基中培养具有产生含有二十二碳六烯酸和/或二十二碳五烯酸的脂质的能力的Ulkenia属的微生物并从培养物中回收所述脂质的步骤。 该方法还可以包括从脂质中分离二十二碳六烯酸和/或二十二碳五烯酸的步骤。

公开(公告)号：EP2308988A1

公开(公告)日：2011-04-13

申请号：EP10181443.2

申请日：1997-12-26

申请人： Suntory Holdings Limited

发明人： Higashiyama, Kenichi ,  Yaguchi, Toshiaki ,  Akimoto, Kengo ,  Shimizu, Sakayu

IPC分类号： C12P7/64 ,  C12N1/14

CPC分类号： C12P7/6427 ,  C12N1/14 ,  C12P7/6472

摘要： A process for controlling the mycelial morphology of a microorganism belonging to the genus Mortierella during culturing and a process for producing unsaturated fatty acids and a lipid containing them by using a culture medium for culturing a microorganism in which phosphate ions, potassium ions, sodium ions, magnesium ions, and calcium ions in the culture medium are in the range of 5 to 60 mM, 5 to 60 mM, 2 to 50 mM, 0.5 to 9 mM, and 0.5 to 12 mM, respectively, characterized in that the microorganism belonging to the genus Mortierella is cultured in a culture medium containing phosphate ions in the range of 5 to 60 mM, potassium ions in the range of 5 to 60 mM, sodium ions in the range of 2 to 50 mM, magnesium ions in the range of 0.5 to 9 mM, and calcium ions in the range of 0.5 to 12 mM, respectively, to produce unsaturated fatty acids and the lipid containing them, and the culture medium for culturing a microorganism having phosphate ions, potassium ions, sodium ions, magnesium ions, and calcium ions in the range of 5 to 60 mM, 5 to 60 mM, 2 to 50 mM, 0.5 to 9 mM, and 0.5 to 12 mM, respectively.

摘要翻译： 一种用于控制属于被孢霉属的微生物的培养过程中的菌丝体的形态和用于生产不饱和脂肪酸的方法和过程的脂质含通过使用用于培养在其中磷酸根离子，钾离子，钠离子的微生物的培养基中培养它们， 镁离子，和在培养基中的钙离子是在5至60毫米，5到60毫米，2至50mM，0.5至9毫米的范围内，和0.5至12mm，分别在DASS模具微生物属于特点 被孢霉属是在培养基中含有磷酸根离子的范围内培养5至60毫米，钾离子的范围为5至60毫米，钠离子在2至50mM的镁离子在0.5的范围内的范围内 至9mm，和在0.5至12mm的范围内的钙离子，分别以产生不饱和脂肪酸和脂质含有它们，以及用于培养微生物具有磷酸根离子，钾离子，钠离子，镁离子的培养基 S，和钙离子在5至60毫米，5到60毫米，2〜分别为50mm，0.5至9毫米，和0.5至12毫米，的范围内。