公开(公告)号：EP2009105A1

公开(公告)日：2008-12-31

申请号：EP08017504.5

申请日：2004-12-28

申请人： SUNTORY LIMITED

发明人： Ooshima, Takashi ,  Nakano, Kazuhiko

IPC分类号： C12N15/31 ,  C12N1/20 ,  C12Q1/68 ,  C12Q1/02 ,  C12P21/08 ,  C07K16/12 ,  G01N33/53 ,  G01N33/569 ,  C12M1/00

CPC分类号： G01N33/56944 ,  C07K14/315

摘要： A polynucleotide encoding a polypeptide which lowers the glucose side chain amount in a serotype-specific polysaccharide antigen of Streptococcus mutans ; novel Streptococcus mutans strain having the above polynucleotide; an antibody specific to this Streptococcus mutans strain; and a method of detecting the above-described Streptococcus mutans strain occurring in a subject sample. According to this method, it is possible to examine the presence or absence of Streptococcus mutans of an untypable serotype in a subject sample to thereby specify a subject having a high risk of the onset of infective endocarditis.

摘要翻译： 编码多肽的多核苷酸，其降低变形链球菌的血清型特异性多糖抗原中的葡萄糖侧链量; 具有上述多核苷酸的新型变形链球菌菌株; 对该变形链球菌菌株特异的抗体; 以及检测在本发明样品中发生的上述变形链球菌菌株的方法。 根据该方法，可以检查受试者样品中不可比血清型变异链球菌的存在或不存在，从而指定感染性心内膜炎发病风险高的受试者。

公开(公告)号：EP1997896A1

公开(公告)日：2008-12-03

申请号：EP07740799.7

申请日：2007-03-27

申请人： Suntory Limited

发明人： ONO, Eiichiro

IPC分类号： C12N15/54 ,  A01H1/00 ,  A01H5/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/10

CPC分类号： C12N9/1007 ,  C12N15/8243

摘要： The present invention relates to genes for enzymes having the activity of transferring a methyl group to lignans, plants with an altered lignan composition using these methyltransferases, and so on. More particularly, the present invention relates to enzyme genes having the activity of synthesizing methylated lignans, preferably enzyme genes having the activity of synthesizing sesame-derived methylated lignans, and use thereof.

摘要翻译： 本发明涉及具有将甲基转移到木脂体的酶的酶的基因，使用这些甲基转移酶的具有改变的木酚素组成的植物等。 更具体地，本发明涉及具有合成甲基化木脂素的活性的酶基因，优选具有合成芝麻衍生的甲基化木脂素的活性的酶基因及其用途。

公开(公告)号：EP1996618A1

公开(公告)日：2008-12-03

申请号：EP06834386.2

申请日：2006-12-05

申请人： SUNTORY LIMITED

发明人： NAKAO, Yoshihiro ,  KODAMA, Yukiko ,  SHIMONAGA, Tomoko

IPC分类号： C07K14/705 ,  C07K14/395 ,  C12C12/00

CPC分类号： C07K14/705 ,  C12C12/004 ,  C12C12/006 ,  C12G1/0203

摘要： The present invention relates to ammonia transporter genes and use thereof. The invention relates in particular to a brewer's yeast which shows enhanced ammonia assimilation, alcoholic beverages produced using such yeast, and a method of producing such alcoholic beverages. More specifically, the invention relates to the MEP1 gene which codes for the ammonia transporter Mep1 in brewer's yeast, particularly to a yeast which can control the ammonia assimilation ability by controlling the level of expression of the nonScMEP1 gene or ScMEP1 gene characteristic to beer yeast and to a method of producing alcoholic beverages using such yeast.

摘要翻译： 本发明涉及氨转运蛋白基因及其用途。 本发明特别涉及显示出增强的氨同化作用的啤酒酵母，使用这种酵母生产的酒精饮料以及生产这种酒精饮料的方法。 更具体地说，本发明涉及编码啤酒酵母中氨转运蛋白Mep1的MEP1基因，特别涉及通过控制啤酒酵母特有的nonScMEP1基因或ScMEP1基因的表达水平来控制氨同化能力的酵母，和 涉及使用这种酵母生产酒精饮料的方法。

公开(公告)号：EP1991670A1

公开(公告)日：2008-11-19

申请号：EP07713914.5

申请日：2007-02-01

申请人： SUNTORY LIMITED

发明人： NAKAO, Yoshihiro, SUNTORY LIMITED ,  KODAMA, Yukiko, SUNTORY LIMITED ,  SHIMONAGA, Tomoko, SUNTORY LIMITED

IPC分类号： C12N9/10 ,  C12C11/00 ,  C12N1/18

CPC分类号： C12C12/006 ,  C12C12/004 ,  C12G1/02 ,  C12N9/90

摘要： The present invention relates to a gene encoding a protein having a trehalose synthesis-promoting activity and use thereof, in particular, a yeast for practical use with superior resistance property to dryness and/or low-temperature storage, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast, whose resistance property to dryness and/or resistance property to low-temperature storage is enhanced by amplifying expression level of TSL1 gene encoding a protein Tsl1p having a trehalose synthesis-promoting activity in brewer's yeast, especially non-ScTSL1 gene specific to a lager brewing yeast and to a method for producing alcoholic beverages with said yeast, etc.

公开(公告)号：EP1964480A1

公开(公告)日：2008-09-03

申请号：EP06842862.2

申请日：2006-12-18

申请人： SUNTORY LIMITED

发明人： NAKAHARA, Koichi ,  SAWADA, Masako ,  YAMADA, Daisuke

IPC分类号： A23L1/10 ,  C12C1/16

CPC分类号： C12C1/16 ,  A23L7/10 ,  A23L7/20 ,  A23L11/20

摘要： A method for processing a sprouted cereal in which an enzymatic activity in the sprouted cereal is reduced by bringing the sprouted cereal into contact with water vapor.

摘要翻译： 一种用于处理在哪一个发芽谷物在发芽谷物的酶活性的方法是通过使发芽谷物和水蒸气接触，降低。

公开(公告)号：EP1959020A1

公开(公告)日：2008-08-20

申请号：EP06823559.7

申请日：2006-12-01

申请人： Suntory Limited ,  Hiroshima University

发明人： KODAMA, Yukiko ,  NAGANO, Hideaki ,  FUNATO, Koichi

IPC分类号： C12P13/00 ,  C12N15/09

CPC分类号： C12P13/02

摘要： The present invention provides methods for producing human ceramide in a yeast cell.
The methods of the present invention comprise:
1) introducing the sphingoid Δ4-desaturase gene (DES1) by transformation of the yeast cell; and
2) abolishing the expression of the yeast sphinganine C4-hydroxylase gene (SUR2) by transformation of the yeast cell.

摘要翻译： 本发明提供了在酵母细胞中生产人神经酰胺的方法。 本发明的方法包括：1）通过转化酵母细胞引入鞘氨醇“4-去饱和酶基因（DES1）”; 和2）通过酵母细胞的转化来消除酵母胞浆素C4-羟化酶基因（SUR2）的表达。

公开(公告)号：EP1938832A1

公开(公告)日：2008-07-02

申请号：EP08153738.3

申请日：2004-03-17

申请人： Suntory Limited

发明人： The designation of the inventor has not yet been filed

IPC分类号： A61K38/55 ,  A61K38/06 ,  C07K5/08

CPC分类号： C07K5/0808 ,  A61K38/00

摘要： It is intended to provide ACE inhibitory tripeptides which are not easily digested by digestive enzymes after being orally taken and thus have fewer tendencies to lose their ACE inhibitory activity in vivo .
More specifically, 3 tripeptides having an ACE inhibitory activity and showing a hypotensive effect in an animal experiment are discovered from a thermolysin digestion product of sesame. These tripeptides respectively have amino acid sequences Leu-Ser-Ala, Val-Ile-Tyr and Leu-Val-Tyr and show an angiotensin converting enzyme inhibitory activity.

公开(公告)号：EP1533313B1

公开(公告)日：2008-07-02

申请号：EP03738665.3

申请日：2003-07-03

申请人： SUNTORY LIMITED

发明人： ISHIKURA, Yoshiyuki ,  TSUJI, Kuniro ,  NUKAYA, Haruo

IPC分类号： C07D493/14 ,  A61K31/352 ,  A61P11/02 ,  A61P17/00 ,  A61P27/14 ,  A61P37/08 ,  A61P43/00 ,  A61K8/60 ,  A61Q5/02 ,  A61Q19/00 ,  A61Q11/00 ,  A23L1/30 ,  A23L2/00 ,  A61K8/18

CPC分类号： A61K8/602 ,  A23L33/11 ,  A23V2002/00 ,  A61K31/352 ,  A61Q5/02 ,  A61Q19/00 ,  C07D493/14 ,  A23V2200/304 ,  A23V2250/2116

摘要： It is intended to provide a novel flavone C-glycoside derivative or its salt showing, in particular, an antiallergic effect and a composition containing the same. Allergic diseases have been increasing in the recent years. Among all, pollenosis and atopic dermatitis are remarkably increasing to thereby result in social problems. Flavones and glycosides thereof, which are reported as having an effect of inhibiting the release of histamine from adipocytes and an immunosuppressive effect, are expected as being applicable as remedies for allergy. However, most of flavones should be taken in a large dose to exert the effects and, therefore, it has been urgently required to find out a compound exhibiting the effects at a smaller dose. Under these circumstances, it is intended to provide a novel component whereby allergic diseases can be treated in a small dose and a composition containing the same.

公开(公告)号：EP1929869A1

公开(公告)日：2008-06-11

申请号：EP06798395.7

申请日：2006-09-28

申请人： SUNTORY LIMITED

发明人： SAEKI, Takeshi ,  KOMURA, Hajime ,  OHWADA, Takuji ,  KINOSHITA, Mikio

IPC分类号： A01N43/72 ,  A01N63/00 ,  A01N63/02 ,  A01P3/00 ,  C07K7/02

CPC分类号： A01N37/46 ,  A01N43/90 ,  A01N63/02 ,  C07K7/06

摘要： The present invention relates to a composition for controlling scab disease in agricultural products, which comprises a compound of Formula I or a salt thereof. The present invention further relates to a method for controlling scab disease in agricultural products by using a composition for controlling scab disease, which comprises a compound of Formula I or a salt thereof.

摘要翻译： 本发明涉及用于控制农产品中的痂病的组合物，其包含式I化合物或其盐。 本发明还涉及通过使用用于控制痂病的组合物来控制农产品中的痂病的方法，其包含式I化合物或其盐。

公开(公告)号：EP1926832A1

公开(公告)日：2008-06-04

申请号：EP06796654.9

申请日：2006-08-16

申请人： SUNTORY LIMITED

发明人： KODAMA, Yukiko ,  HATANAKA, Kazushige ,  TANAKA, Koichi ,  NAKAGAWA, Hiroko ,  MORIYA, Shogo ,  OSANO, Kaoru

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6895 ,  C12Q1/6888

摘要： The present invention relates to an instrument, a method and a kit for detecting a microorganism contaminating a subject test sample, which enables one to quickly and accurately identify the microorganism with an easy operation. The instrument for detecting a microorganism according to the present invention relates to a microarray type instrument in which oligonucleotides prepared based on nucleotide sequences specific to the species and genus to which the subject microorganism belongs have been immobilized onto a surface of a substrate. Based on the presence or absence of hybridization of the probes prepared from the test sample with the oligonucleotides immobilized onto the surface of the substrate, the present invention makes it possible to detect and/or identify the microorganism in the test sample easily, quickly and accurately.