公开(公告)号：EP4279596A1

公开(公告)日：2023-11-22

申请号：EP21919587.2

申请日：2021-11-30

申请人： National University Corporation Tokai National Higher Education and Research System

发明人： KASUYA, Hideki ,  NAOE, Yoshinori ,  MATSUMURA, Shigeru ,  EISSA, Ibrahim Ragab Nassr ,  ALI MOHAMED, Mohamed Abdelmoneim Ahmed

IPC分类号： C12N15/62 ,  A61K35/12 ,  A61K35/15 ,  A61K39/395 ,  A61P31/00 ,  A61P35/00 ,  A61P37/06 ,  A61P37/08 ,  C07K14/705 ,  C07K16/18 ,  C07K16/28 ,  C07K16/30 ,  C07K16/32 ,  C07K19/00 ,  C12N5/0784 ,  C12N5/0786 ,  C12N5/10 ,  C12N15/12 ,  C12N15/13

摘要： Provided is a chimeric target factor receptor capable of activating an antigen-presenting cell such as a dendritic cell in a target-factor-specific manner. The chimeric target factor receptor contains a target factor-binding domain, a transmembrane domain, and an intracellular domain containing a TLR intracellular domain.