公开(公告)号：EP2814473A1

公开(公告)日：2014-12-24

申请号：EP13703834.5

申请日：2013-02-14

申请人： NeuroSearch A/S

发明人： HANSEN, Henrik Björk ,  GRUNNET, Morten ,  BENTZEN, Bo Hjorth ,  HYVELED-NIELSEN, Lars ,  LASSEN, Jørgen Buus ,  SUNDGREEN, Claus

IPC分类号： A61K31/135 ,  A61K31/46 ,  A61P3/04 ,  A61P9/00 ,  A61P3/00 ,  A61P9/10 ,  A61P3/10

CPC分类号： A61K31/138 ,  A61K31/135 ,  A61K31/46 ,  A61K2300/00

摘要： This invention relates to the use of pharmaceutical compositions comprising a therapeutically effective combination of Tesofensine and Metoprolol for preventing the cardiovascular side effects of Tesofensine, while leaving the robust inhibitory efficacy on food intake and body weight loss unaffected.