公开(公告)号：EP4285743A3

公开(公告)日：2024-02-14

申请号：EP23196794.4

申请日：2020-09-10

Applicant: Nicoventures Trading Limited

Inventor： POOLE, Thomas H. ,  KELLER, Christopher ,  KEYSER, Brian Michael ,  MOLDOVEANU, Serban C.

IPC: A24B13/00 ,  A24B15/10

Abstract: The disclosure provides compositions configured for oral use, the compositions including at least one filler, water, a basic amine, and an organic acid, an alkali metal salt of an organic acid, or a combination thereof, wherein the organic acid has a logP value of from about 1.4 to about 8.0. At least a portion of the basic amine is associated with at least a portion of the organic acid or the alkali metal salt thereof. The association is in the form of a basic amine-organic acid salt, an ion pair between the basic amine and a conjugate base of the organic acid, or a combination of both. Further provided are methods for stabilizing a composition configured for oral use and for enhancing a predicted buccal absorption of a composition configured for oral use.

公开(公告)号：EP4304569A1

公开(公告)日：2024-01-17

申请号：EP22711626.6

申请日：2022-03-10

Applicant: Nicoventures Trading Limited

Inventor： POOLE, Thomas H. ,  DANIEL, Michael S.

IPC: A61K9/68 ,  A61K31/05 ,  A61K9/107

公开(公告)号：EP4072328A1

公开(公告)日：2022-10-19

申请号：EP20820559.1

申请日：2020-12-02

Applicant: Nicoventures Trading Limited

Inventor： POOLE, Thomas H. ,  ALDERMAN, Steven Lee ,  GERARDI, Anthony Richard

IPC: A24B13/00 ,  A24B15/30 ,  A61K31/352

公开(公告)号：EP4027811A1

公开(公告)日：2022-07-20

申请号：EP20772433.7

申请日：2020-09-10

Applicant: Nicoventures Trading Limited

Inventor： KELLER, Christopher ,  POOLE, Thomas H. ,  HUTCHENS, Ronald K. ,  GERARDI, Anthony R.

IPC: A24B13/00 ,  A24B15/16 ,  A24B15/30

公开(公告)号：EP4408183A1

公开(公告)日：2024-08-07

申请号：EP22790046.1

申请日：2022-09-29

Applicant: Nicoventures Trading Limited

Inventor： TANG, Kai ,  ALDERMAN, Steven Lee ,  POOLE, Thomas H. ,  ZAWADZKI, Michael

IPC: A23G4/00 ,  A24B15/16 ,  A61K9/00

CPC classification number: A24B15/16 ,  A61K9/0056 ,  A24B13/00 ,  A24B15/30 ,  A61K47/12 ,  A61K47/20 ,  A61K47/38 ,  A61K47/36 ,  A61K47/26 ,  A61K47/22 ,  A61K47/10 ,  A23G4/12 ,  A23G3/364

公开(公告)号：EP4326096A1

公开(公告)日：2024-02-28

申请号：EP22720786.7

申请日：2022-04-21

Applicant: Nicoventures Trading Limited

Inventor： VON COSMOS, Nicolas ,  LAMPE, Matthew ,  ALDERMAN, Steven Lee ,  POOLE, Thomas H. ,  ZAWADZKI, Michael Andrew ,  SMITH, Charlotte ,  SIEVERT, James

IPC: A24B13/00 ,  A24B15/16

公开(公告)号：EP4326095A1

公开(公告)日：2024-02-28

申请号：EP22720785.9

申请日：2022-04-21

Applicant: Nicoventures Trading Limited

Inventor： ALDERMAN, Steven Lee ,  POOLE, Thomas H. ,  JOYCE, Michael ,  JONES, Wesley Steven ,  LAMPE, Matthew ,  ZAWADZKI, Michael Andrew

IPC: A24B13/00 ,  A24B15/10 ,  A24B15/30

公开(公告)号：EP4285743A2

公开(公告)日：2023-12-06

申请号：EP23196794.4

申请日：2020-09-10

Applicant: Nicoventures Trading Limited

Inventor： POOLE, Thomas H. ,  KELLER, Christopher ,  KEYSER, Brian Michael ,  MOLDOVEANU, Serban C.

IPC: A24B15/10

Abstract: The disclosure provides compositions configured for oral use, the compositions including at least one filler, water, a basic amine, and an organic acid, an alkali metal salt of an organic acid, or a combination thereof, wherein the organic acid has a logP value of from about 1.4 to about 8.0. At least a portion of the basic amine is associated with at least a portion of the organic acid or the alkali metal salt thereof. The association is in the form of a basic amine-organic acid salt, an ion pair between the basic amine and a conjugate base of the organic acid, or a combination of both. Further provided are methods for stabilizing a composition configured for oral use and for enhancing a predicted buccal absorption of a composition configured for oral use.

公开(公告)号：EP4072527A1

公开(公告)日：2022-10-19

申请号：EP20845438.9

申请日：2020-12-08

Applicant: Nicoventures Trading Limited

Inventor： HUTCHENS, Ronald K. ,  KELLER, Christopher ,  POOLE, Thomas H. ,  BEESON, Dwayne William ,  ST. CHARLES, Frank Kelley ,  HOLTON, Darrell Eugene, Jr.

IPC: A61K9/00 ,  A61K31/495 ,  A61K31/465

公开(公告)号：EP4072351A1

公开(公告)日：2022-10-19

申请号：EP20899707.2

申请日：2020-12-08

Applicant: Nicoventures Trading Limited

Inventor： BEESON, Dwayne William ,  BUNCH, John E. ,  GERARDI, Anthony Richard ,  GRIMES, Chris J. ,  HUTCHENS, Ronald K. ,  KELLER, Christopher ,  POOLE, Thomas H. ,  RIGGINS, Allen ,  ST. CHARLES, Frank Kelley ,  STOKES, Cynthia ,  HOLTON, Darrell Eugene, Jr.

IPC: A24B13/00 ,  A24B15/16 ,  A24B15/24 ,  A24B15/28 ,  A24B15/30 ,  A61K9/00 ,  A61K31/465 ,  A61K9/16 ,  B65D65/38 ,  D04H1/70