公开(公告)号：EP0839035B1

公开(公告)日：2002-10-02

申请号：EP96922243.9

申请日：1996-07-05

申请人： Nihon Nohyaku Co., Ltd.

发明人： KODAMA, Hiroki ,  NIWANO, Yoshimi ,  KANAI, Kazuo ,  YOSHIDA, Masanori

IPC分类号： A61K31/415 ,  A61P31/10

CPC分类号： C07D231/12 ,  A61K31/4178 ,  C07D233/56 ,  C07D249/08

摘要： R-(+)-(E)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile, R-(-)-(E)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile, and pharmaceutically acceptable salts thereof which can be used as a pharmaceutical agent are disclosed. A process for producing them and a method for treating mycoses using them are also disclosed.

公开(公告)号：EP0839035A2

公开(公告)日：1998-05-06

申请号：EP96922243.0

申请日：1996-07-05

申请人： Nihon Nohyaku Co., Ltd.

发明人： KODAMA, Hiroki ,  NIWANO, Yoshimi ,  KANAI, Kazuo ,  YOSHIDA, Masanori

IPC分类号： A61K31 ,  A61P31 ,  C07D521

CPC分类号： C07D231/12 ,  A61K31/4178 ,  C07D233/56 ,  C07D249/08

摘要： R-(+)-(E)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile, R-(-)-(E)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1-imidazolylacetonitrile, and pharmaceutically acceptable salts thereof which can be used as a pharmaceutical agent are disclosed. A process for producing them and a method for treating mycoses using them are also disclosed.