公开(公告)号：EP4205736A1

公开(公告)日：2023-07-05

申请号：EP22767147.6

申请日：2022-03-08

申请人： Niigata University ,  Denka Company Limited

发明人： SAITO, Akihiko ,  GOTO, Sawako ,  HIRAYAMA, Yoshiaki

IPC分类号： A61K31/201 ,  A61P13/12 ,  A61P43/00

摘要： One object of the present invention is to provide an inhibitor for renal injuries induced by a hemolytic reaction. In this invention, cilastatin or a pharmaceutically acceptable salt thereof is used.

公开(公告)号：EP4230200A1

公开(公告)日：2023-08-23

申请号：EP22767148.4

申请日：2022-03-08

申请人： Niigata University ,  Denka Company Limited

发明人： SAITO, Akihiko ,  GOTO, Sawako ,  HIRAYAMA, Yoshiaki

IPC分类号： A61K31/201 ,  A61P13/12 ,  A61P43/00

摘要： One object of the present invention is to provide an inhibitor for renal injuries induced by rhabdomyolysis. In this invention, cilastatin or a pharmaceutically acceptable salt thereof is used.

公开(公告)号：EP4186515A1

公开(公告)日：2023-05-31

申请号：EP21845355.3

申请日：2021-07-16

申请人： Niigata University ,  Denka Company Limited

发明人： SAITO, Akihiko ,  GOTO, Sawako ,  HIRAYAMA, Yoshiaki

IPC分类号： A61K31/714 ,  A61K31/201 ,  A61P13/12 ,  A61P43/00

摘要： One object of the present invention is to provide an inhibitor for renal injuries induced by an iodinated contrast medium. In this invention, vitamin B 12 or a pharmaceutically acceptable salt thereof is used.

公开(公告)号：EP3785711A1

公开(公告)日：2021-03-03

申请号：EP19794059.6

申请日：2019-04-26

申请人： Niigata University ,  Denka Company Limited

发明人： SAITO, Akihiko ,  GOTO, Sawako ,  HIRAYAMA, Yoshiaki ,  SEKINE, Sakari

IPC分类号： A61K31/198 ,  A61P13/12 ,  A61K49/04

摘要： One object of the present invention is to provide an inhibitor for renal injuries induced by an iodinated contrast medium. In this invention, cilastatin or a pharmaceutically acceptable salt thereof is used.