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1.发明授权
公开(公告)号：EP3077016B1
公开(公告)日：2018-05-16
申请号：EP14827588.6
申请日：2014-12-02
申请人： Novartis AG
发明人： JIANG, Xuwei , SCHLUETER, Douglas , LAREDO, Walter
CPC分类号： A61L27/16 , A61F2/14 , A61F2/16 , A61F2/18 , A61L27/18 , A61L27/50 , A61L2430/16 , C08F220/30 , C08F236/02 , C08F2220/286
摘要： High refractive index acrylic device materials with reduced glistenings are disclosed. The device materials are particularly suitable for use as ophthalmic or otorhhinolaryngological device materials and comprises a poly(phenyl ether)-containing monomer and/or a poly(phenyl ether)-containing cross-linking agent.
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2.发明公开
公开(公告)号：EP3077016A1
公开(公告)日：2016-10-12
申请号：EP14827588.6
申请日：2014-12-02
申请人： Novartis AG
发明人： JIANG, Xuwei , SCHLUETER, Douglas , LAREDO, Walter
CPC分类号： A61L27/16 , A61F2/14 , A61F2/16 , A61F2/18 , A61L27/18 , A61L27/50 , A61L2430/16 , C08F220/30 , C08F236/02 , C08F2220/286
摘要： High refractive index acrylic device materials with reduced glistenings are disclosed. The device materials are particularly suitable for use as ophthalmic or otorhhinolaryngological device materials and comprises a poly(phenyl ether)-containing monomer and/or a poly(phenyl ether)-containing cross-linking agent.
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公开(公告)号：EP3419961A1
公开(公告)日：2019-01-02
申请号：EP17709806.8
申请日：2017-02-16
申请人： Novartis AG
IPC分类号： C07C225/22 , C07C233/33 , C07C235/84
摘要： Described herein are UV-absorbing vinylic monomers and their uses in preparing UV-absorbing contact lenses capable of blocking ultra-violet (“UV”) radiation and violet radiation with wavelengths from 380 nm to 440 nm, thereby protecting eyes to some extent from damages caused by UV radiation and potentially from violet radiation.
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公开(公告)号：EP3077429B1
公开(公告)日：2018-09-26
申请号：EP14816036.9
申请日：2014-12-02
申请人： Novartis AG
发明人： JIANG, Xuwei , SCHLUETER, Douglas
IPC分类号： C08F220/24
CPC分类号： A61L27/16 , A61F2/1624 , C08F220/18 , C08F220/24 , C08F222/10 , C08F222/1006 , G02B1/043 , C08L33/08 , C08L33/10 , C08F2220/1825 , C08F2220/1858 , C08F2222/1013
摘要： Soft hydrophobic acrylic materials with improved resistance to fluid diffusion and suitable mechanical properties that allow deformation upon application of force are disclosed. The acrylic materials are particularly suitable for use in fluid-based accommodating intraocular lenses and comprises combination of a perfluoro-substituted alkyl (meth)acrylate and an alkyl (meth)acrylate, and a cross-linking agent.
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5.发明公开LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES 审中-公开用于眼科装置的低含水量丙烯酸酯 - 丙烯酰胺共聚物
公开(公告)号：EP3200840A1
公开(公告)日：2017-08-09
申请号：EP15828575.9
申请日：2015-12-14
申请人： Novartis AG
发明人： LAREDO, Walter , AKINAY, Ali E. , JIANG, Xuwei , JINKERSON, David , NGUYEN, Vincent , SCHLUETER, Douglas
CPC分类号： G02B1/043 , A61L27/26 , A61L27/50 , A61L27/52 , A61L2430/16 , G02B1/041 , C08L33/26 , A61L2/26
摘要： Acrylate-acrylamide copolymers are disclosed. They are rigid and glassy in dry state at room temperature (from about 23° C. to about 28° C.), but are soft and very deformable and have a high refractive index, a high glistening resistance and a low aging-related surface light scattering in fully hydrated state. They are particularly suitable for making wet-packed intraocular lenses (IOLs) which can be delivered through sub 2.0 mm incisions.
摘要翻译： 公开了丙烯酸酯 - 丙烯酰胺共聚物。 它们在室温下（约23℃至约28℃）在干燥状态下是刚性和玻璃状的，但是柔软并且非常易变形并且具有高折射率，高抗闪光性和低老化相关表面 在完全水合状态下的光散射。 它们特别适用于制造可通过2.0毫米以下切口输送的湿式眼内透镜（IOL）。
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公开(公告)号：EP3200839B1
公开(公告)日：2019-09-04
申请号：EP15828574.2
申请日：2015-12-14
申请人： Novartis AG
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公开(公告)号：EP2673666B1
公开(公告)日：2014-12-31
申请号：EP12706743.7
申请日：2012-02-07
申请人： Novartis AG
发明人： LAREDO, Walter R. , JIANG, Xuwei
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08L83/04 , C08L51/085 , C08L33/08
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公开(公告)号：EP3223870B1
公开(公告)日：2018-09-26
申请号：EP16704741.4
申请日：2016-01-26
申请人： Novartis AG
发明人： JIANG, Xuwei , SCHLUETER, Douglas , LAREDO, Walter
CPC分类号： A61L27/16 , A61F2/16 , A61L27/18 , A61L27/26 , A61L27/50 , A61L2430/16 , C08F220/30 , C08F2220/305
摘要： Intraocular lens materials are disclosed. They are soft and very deformable and have a high refractive index, and a high glistening resistance in fully hydrated state. They are particularly suitable for making wet-packed intraocular lenses (IOLs) which can be delivered through sub 2.0 mm incisions.
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公开(公告)号：EP3223870A1
公开(公告)日：2017-10-04
申请号：EP16704741.4
申请日：2016-01-26
申请人： Novartis AG
发明人： JIANG, Xuwei , SCHLUETER, Douglas , LAREDO, Walter
CPC分类号： A61L27/16 , A61F2/16 , A61L27/18 , A61L27/26 , A61L27/50 , A61L2430/16 , C08F220/30 , C08F2220/305
摘要： Intraocular lens materials are disclosed. They are soft and very deformable and have a high refractive index, and a high glistening resistance in fully hydrated state. They are particularly suitable for making wet-packed intraocular lenses (IOLs) which can be delivered through sub 2.0 mm incisions.
摘要翻译： 公开了人工晶状体材料。 它们柔软且变形大，折射率高，在完全水合状态下具有高闪光抗性。 它们特别适用于制造可通过2.0毫米以下切口输送的湿式眼内透镜（IOL）。
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10.发明公开
公开(公告)号：EP3200839A1
公开(公告)日：2017-08-09
申请号：EP15828574.2
申请日：2015-12-14
申请人： Novartis AG
发明人： LAREDO, Walter , AKINAY, Ali E. , JIANG, Xuwei , JINKERSON, David , NGUYEN, Vincent , SCHLUETER, Douglas
摘要： Acrylate-acrylamide copolymers are disclosed. They are rigid and glassy in dry state at room temperature (from about 23° C. to about 28° C.), but are soft and very deformable and have a high refractive index, a high glistening resistance and a low aging-related surface light scattering in fully hydrated state. They are particularly suitable for making wet-packed intraocular lenses (IOLs) which can be delivered through sub 2.0 mm incisions.
摘要翻译： 公开了丙烯酸酯 - 丙烯酰胺共聚物。 它们在室温下（约23℃至约28℃）在干燥状态下是刚性和玻璃状的，但是柔软并且非常易变形并且具有高折射率，高抗闪光性和低老化相关表面 在完全水合状态下的光散射。 它们特别适用于制造可通过2.0毫米以下切口输送的湿式眼内透镜（IOL）。
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