专利检索 ap:("Novartis AG") AND inv:"MANNING, James R." 第 1 页

1.

发明公开
FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS 审中-实审

公开(公告)号：EP4356969A3

公开(公告)日：2024-05-22

申请号：EP23217305.4

申请日：2017-08-25

申请人： Novartis AG

发明人： JAIN, Rama , KOESTER, Dennis Christofer , MANNING, James R. , MARX, Vanessa , POON, Daniel , SUTTON, James Clifford , TAFT, Benjamin R. , WAN, Lifeng , YIFRU, Aregahegn , ZHAO, Qian

IPC分类号： C07D471/14 , C07D487/14 , C07D498/14 , A61K31/5025 , A61K31/53 , A61P31/14 , A61P31/16

CPC分类号： C07D471/14 , C07D487/14 , C07D498/14 , A61P31/14 , A61P31/16

摘要： The invention provides compounds of Formula (I): (I) as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

2.

发明公开
INDOLE-2-CARBONYL COMPOUNDS AND THEIR USE FOR THE TREATMENT OF HEPATITIS B 审中-公开

公开(公告)号：EP3759110A1

公开(公告)日：2021-01-06

申请号：EP19713573.4

申请日：2019-02-26

申请人： Novartis AG

发明人： FU, Jiping , JAIN, Rama , JIN, Xianming , LIN, Xiaodong , LINDVALL, Mika , MANNING, James R. , MCENROE, Glenn

IPC分类号： C07D487/04 , A61P31/12 , A61K31/4985

3.

发明公开
FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS 审中-公开

公开(公告)号：EP3504214A1

公开(公告)日：2019-07-03

申请号：EP17771587.7

申请日：2017-08-25

申请人： Novartis AG

发明人： JAIN, Rama , KOESTER, Dennis Christofer , MANNING, James R. , MARX, Vanessa , POON, Daniel , SUTTON, James Clifford , TAFT, Benjamin R. , WAN, Lifeng , YIFRU, Aregahegn , ZHAO, Qian

IPC分类号： C07D487/14 , A61K31/5025 , A61K31/53 , A61P31/16

4.

发明公开
10-(DI(PHENYL)METHYL)-4-HYDROXY-8,9,9A,10-TETRAHYDRO-7H-PYRROLO[1 ',2':4,5]PYRAZINO[1,2-B]PYRIDAZINE-3,5-DIONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE ORTHOMYXOVIRUS REPLICATION FOR TREATING INFLUENZA 审中-公开

公开(公告)号：EP3759113A1

公开(公告)日：2021-01-06

申请号：EP19713572.6

申请日：2019-02-26

申请人： Novartis AG

发明人： DAUPHINAIS, Maxime , JAIN, Rama , KOESTER, Dennis Christofer , MANNING, James R. , MARX, Vanessa , POON, Daniel , WAN, Lifeng , WANG, Xiaojing Michael , YIFRU, Aregahegn , ZHAO, Qian

IPC分类号： C07D487/14 , C07D498/14 , A61K31/4985 , A61K31/5025 , A61P31/16

5.

发明公开
TRICYCLIC COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS 审中-公开

公开(公告)号：EP3426656A1

公开(公告)日：2019-01-16

申请号：EP17711349.5

申请日：2017-03-07

申请人： Novartis AG

发明人： JAIN, Rama , KOESTER, Dennis Christofer , MANNING, James R. , SUTTON, James Clifford , TAFT, Benjamin R. , WAN, Lifeng , ZHAO, Qian

IPC分类号： C07D471/14 , C07D487/14 , C07D491/22 , C07D498/14 , A61K31/5025 , A61P31/16

6.

发明公开
PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF 审中-公开

公开(公告)号：EP4308562A1

公开(公告)日：2024-01-24

申请号：EP22711643.1

申请日：2022-03-14

申请人： Novartis AG

发明人： BONAZZI, Simone , CERNIJENKO, Artiom , COBB, Jennifer Stroka , DALES, Natalie Alysia , DEWHURST, Janetta , HESSE, Matthew James , JAIN, Rama , KERRIGAN, John Ryan , MALIK, Hasnain Ahmed , MANNING, James R. , O'BRIEN, Gary , PATTERSON, Andrew W. , THOMSEN, Noel Marie-France , TING, Pamela YF

IPC分类号： C07D471/04 , C07D498/04 , A61K31/437 , A61P7/00

7.

发明授权
FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS 有权

公开(公告)号：EP3504214B1

公开(公告)日：2020-12-02

申请号：EP17771587.7

申请日：2017-08-25

申请人： Novartis AG

发明人： JAIN, Rama , KOESTER, Dennis Christofer , MANNING, James R. , MARX, Vanessa , POON, Daniel , SUTTON, James Clifford , TAFT, Benjamin R. , WAN, Lifeng , YIFRU, Aregahegn , ZHAO, Qian

IPC分类号： C07D487/14 , A61K31/5025 , A61K31/53 , A61P31/16

8.

发明公开
NOVEL DIHYDROISOXAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF HEPATITIS B 审中-公开

公开(公告)号：EP3710455A1

公开(公告)日：2020-09-23

申请号：EP18812295.6

申请日：2018-11-16

申请人： Novartis AG

发明人： FU, Jiping , LINDVALL, Mika , MANNING, James R. , MCENROE, Glenn

IPC分类号： C07D498/04 , A61P31/14 , A61K31/424

9.

发明公开
FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS 审中-实审

公开(公告)号：EP4356969A2

公开(公告)日：2024-04-24

申请号：EP23217305.4

申请日：2017-08-25

申请人： Novartis AG

发明人： JAIN, Rama , KOESTER, Dennis Christofer , MANNING, James R. , MARX, Vanessa , POON, Daniel , SUTTON, James Clifford , TAFT, Benjamin R. , WAN, Lifeng , YIFRU, Aregahegn , ZHAO, Qian

IPC分类号： A61P31/16

CPC分类号： C07D471/14 , C07D487/14 , C07D498/14 , A61P31/14 , A61P31/16

摘要： The invention provides compounds of Formula (I): (I) as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

10.

发明公开
GLUE DEGRADERS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：EP4031243A1

公开(公告)日：2022-07-27

申请号：EP20785841.6

申请日：2020-09-16

申请人： Novartis AG

发明人： AXFORD, Jake , BECKWITH, Rohan Eric John , BONAZZI, Simone , BUSCHMANN, Nicole , CERNIJENKO, Artiom , DEWHURST, Janetta , FAZAL, Aleem , HESSE, Matthew James , HOLDER, Lauren , HORNAK, Viktor , IMASE, Hidetomo , JAIN, Rama , JIN, Xianming , KERRIGAN, John Ryan , LACHAL, Julie , MA, Fupeng , MALIK, Hasnain Ahmed , MANNING, James R. , MCKAY, Daniel , MOREAU, Robert Joseph , NIMSGERN, Pierre , O'BRIEN, Gary , VULPETTI, Anna , YAMADA, Ken , ZHAO, Junping

IPC分类号： A61P25/00 , A61P35/00 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/04 , C07D413/12 , C07D471/04 , C07D401/04 , C07D403/04 , A61K31/513