公开(公告)号：EP1332137A2

公开(公告)日：2003-08-06

申请号：EP01988712.4

申请日：2001-10-26

申请人： Novartis AG ,  Novartis Erfindungen Verwaltungsgesellschaft M.B.H.

发明人： BUCHDUNGER, Elisabeth ,  CAPDEVILLE, Renaud ,  DEMETRI, George, Daniel ,  DIMITRIJEVIC, Sasa ,  DRUKER, Brian, J. ,  FLETCHER, Jonathan, A. ,  JOENSUU, Heikki,c/oHelsinki Univ Central Hospital ,  SILBERMAN, Sandra, Leta ,  TUVESON, David ,  HEINRICH, Michael, C.

IPC分类号： C07D241/00

CPC分类号： C07D401/04 ,  A61K31/506

摘要： 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of the formula (I) or a pharmaceutically acceptable salt thereof can be used in the treatment of gastrointestinal stromal tumours.

公开(公告)号：EP1332137B1

公开(公告)日：2006-03-29

申请号：EP01988712.4

申请日：2001-10-26

申请人： Novartis AG ,  Novartis Pharma GmbH

发明人： BUCHDUNGER, Elisabeth ,  CAPDEVILLE, Renaud ,  DEMETRI, George, Daniel ,  DIMITRIJEVIC, Sasa ,  DRUKER, Brian, J. ,  FLETCHER, Jonathan, A. ,  JOENSUU, Heikki, c/oHelsinki Univ Central Hospital ,  SILBERMAN, Sandra, Leta ,  TUVESON, David ,  HEINRICH, Michael, C.

IPC分类号： A61K31/506 ,  A61P35/00

CPC分类号： C07D401/04 ,  A61K31/506

摘要： 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide of the formula (I) or a pharmaceutically acceptable salt thereof can be used in the treatment of gastrointestinal stromal tumours.