公开(公告)号：EP0954571B1

公开(公告)日：2007-08-29

申请号：EP97920679.4

申请日：1997-04-14

申请人： Novartis AG ,  Novartis Pharma GmbH

发明人： GHISALBA, Oreste ,  KITTELMANN, Matthias ,  LAUMEN, Kurt ,  WALSER-VOLKEN, Paula

IPC分类号： C12N9/80 ,  C12P41/00

CPC分类号： C12N9/80 ,  C12P41/007 ,  Y10S435/826 ,  Y10S435/893 ,  Y10S435/908

摘要： The invention belongs to the field of biotechnology. It concerns a biocatalyst, i.e. a dead or living microorganism or a polypeptide, preferably in isolated form, which exhibits acylase enzymatic activity without lipase- or esterase-activity. The biocatalyst is capable of stereoselectively hydrolysing a racemic acylamide which has an aliphatic acyl residue and which is not a derivative of a natural amino acid.

公开(公告)号：EP0954571A1

公开(公告)日：1999-11-10

申请号：EP97920679.0

申请日：1997-04-14

申请人： Novartis AG ,  Novartis-Erfindungen Verwaltungsgesellschaft m.b.H.

发明人： GHISALBA, Oreste ,  KITTELMANN, Matthias ,  LAUMEN, Kurt ,  WALSER-VOLKEN, Paula

IPC分类号： C12N9 ,  C12P41 ,  C12R1

CPC分类号： C12N9/80 ,  C12P41/007 ,  Y10S435/826 ,  Y10S435/893 ,  Y10S435/908

摘要： The invention belongs to the field of biotechnology. It concerns a biocatalyst, i.e. a dead or living microorganism or a polypeptide, preferably in isolated form, which exhibits acylase enzymatic activity without lipase- or esterase-activity. The biocatalyst is capable of stereoselectively hydrolysing a racemic acylamide which has an aliphatic acyl residue and which is not a derivative of a natural amino acid.