专利检索 ap:("Novartis AG" OR "Novartis Pharma GmbH") AND inv:"YELESWARAPU, Lakshmi" 第 1 页

1.

发明公开
USE OF ALPHA-TUBULIN ACETYLATION LEVELS AS A BIOMARKER FOR PROTEIN DEACETYLASE INHIBITORS 审中-公开
标题翻译： ALPHA-微管蛋白乙酰ALS BIOANZEIGER用于蛋白质去乙酰化酶抑制剂的用途

公开(公告)号：EP1456664A1

公开(公告)日：2004-09-15

申请号：EP02795117.7

申请日：2002-12-06

申请人： Novartis AG , Novartis Pharma GmbH

发明人： ATADJA, Peter, Wisdom , HOVING, Sjouke , TOWBIN, Harry , WALKER, Heather Brownlee , WARTMANN, Markus , YELESWARAPU, Lakshmi

IPC分类号： G01N33/574 , G01N33/50 , G01N33/68 , G01N33/53

CPC分类号： G01N33/5011 , G01N33/574 , G01N2333/916 , G01N2500/10

摘要： The invention relates to a novel method for evaluating the antiproliferative activity of protein deacetylase inhibiting compounds and microtubule interacting agents, as well as a method for screening for compounds that inhibit cell growth or growth of tumors. The invention additionally provides a method for monitoring the progress of treatment against cellular growth or the growth of tumors.