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公开(公告)号：EP1272163A2
公开(公告)日：2003-01-08
申请号：EP01923719.7
申请日：2001-04-09
发明人： AMBÜHL, Michael , HAEBERLIN, Barbara , LÜCKEL, Barbara , MEINZER, Armin , LAMBERT, Olivier , MARCHAL, Laurent
CPC分类号： A61K9/1075 , A61K9/1617 , A61K9/1652 , A61K38/13
摘要： The present invention provides a pharmaceutical composition in solid form comprising a poorly water soluble drug, a solubilizing component, and a surfactant which is semisolid or solid. The poorly soluble drug may e.g. be a cyclosporing or a macrolide.
摘要翻译： 本发明提供固体形式的药物组合物，其包含水难溶性药物，增溶组分和半固体或固体表面活性剂。 难溶药物可能例如 是环孢素或大环内酯。
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公开(公告)号：EP0988046A1
公开(公告)日：2000-03-29
申请号：EP98904156.1
申请日：1998-01-28
发明人： MEINZER, Armin , HAEBERLIN, Barbara
CPC分类号： A61K9/1075 , A61K9/4858 , A61K9/4866 , A61K38/13 , Y10S514/962
摘要： The present invention provides a hard gelatine capsule containing a pharmaceutical composition comprising cyclosporin A in a mixture with a surfactant of HLB value at least 10, substantially free of any oil and when a hydrophilic phase is present, the hydrophilic phase being a polyethylene glycol and/or a lower alkanol provided that any lower alkanol present is present in less than 12 % of the total weight of the composition absent the hard gelatine capsule.
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公开(公告)号：EP0839028A2
公开(公告)日：1998-05-06
申请号：EP96925741.0
申请日：1996-07-12
CPC分类号： A61K31/4745 , A61K9/145 , A61K9/146 , A61K31/436 , A61K31/445 , Y10S514/885 , Y10S514/922 , Y10S514/95 , Y10S514/964 , Y10S514/97
摘要： A pharmaceutical composition in the form of a solid dispersion comprising a macrolide, e.g. a rapamycin or an ascomycin, and a carrier medium.
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公开(公告)号：EP0892640B1
公开(公告)日：2004-02-11
申请号：EP97919330.7
申请日：1997-04-10
申请人： Novartis AG , Novartis Pharma GmbH
IPC分类号： A61K31/365
CPC分类号： A61K31/365 , A61K9/4891 , A61K38/13 , Y10S514/885 , Y10S514/96 , Y10S514/962 , Y10S514/968 , A61K2300/00
摘要： This invention provides a pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to release mycophenolate in the upper part of the intestinal tract.
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公开(公告)号：EP0839028B1
公开(公告)日：2004-01-28
申请号：EP96925741.9
申请日：1996-07-12
申请人： Novartis AG , Novartis Pharma GmbH
IPC分类号： A61K9/14
CPC分类号： A61K31/4745 , A61K9/145 , A61K9/146 , A61K31/436 , A61K31/445 , Y10S514/885 , Y10S514/922 , Y10S514/95 , Y10S514/964 , Y10S514/97
摘要： A pharmaceutical composition in the form of a solid dispersion comprising a macrolide, e.g. a rapamycin or an ascomycin, and a carrier medium.
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公开(公告)号：EP2244692A2
公开(公告)日：2010-11-03
申请号：EP09701184.5
申请日：2009-01-09
申请人： Schering Corporation , Novartis AG
IPC分类号： A61K9/00 , A61K31/167 , A61K31/58 , A61P11/06
CPC分类号： A61K9/008 , A61K31/167 , A61K31/58
摘要： Various embodiments of the present invention provide drug products, inhalation systems and methods of treating respiratory diseases. Several embodiments provide an inhalation system including a pressurized metered dose inhaler and a chamber. The chamber may be an anti-static chamber with a chamber volume of about 145 milliliters (ml) to about 200 ml.
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公开(公告)号：EP2037879A1
公开(公告)日：2009-03-25
申请号：EP07764925.9
申请日：2007-06-28
申请人： Novartis AG , NOVARTIS-PHARMA GMBH
发明人： HAEBERLIN, Barbara , STOWASSER, Frank , WIRTH, Wolfgang , BAUMBERGER, Anton , ABEL, Stephan , KAERGER, Sebastian , KIECKBUSCH, Thomas
CPC分类号： A61K9/1617 , A61K9/0075 , A61K9/145 , A61K9/1688 , A61K31/40 , A61K45/06 , A61K47/12 , A61K2300/00
摘要： A process for preparing dry powder formulations of a glycopyrronium salt for inhalation that have good stability. The process involves (a) micronising a glycopyrronium salt together with' an anti-adherent agent, and (b) admixing carrier particles to form the dry powder formulation.
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公开(公告)号：EP1954267A1
公开(公告)日：2008-08-13
申请号：EP06818680.8
申请日：2006-11-20
申请人： Novartis AG
CPC分类号： A61K9/0075 , A61K9/0078 , A61K9/008 , A61K31/40 , A61K31/58 , A61K2300/00
摘要： Medicaments comprising (A) an antimuscarinic agent and (B) a corticosteroid for the treatment of inflammatory or obstructive airways diseases.
摘要翻译： 包含（A）抗毒蕈碱剂和（B）皮质类固醇的药物，用于治疗炎性或阻塞性气道疾病。
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公开(公告)号：EP2037879B1
公开(公告)日：2013-05-15
申请号：EP07764925.9
申请日：2007-06-28
申请人： Novartis AG
发明人： HAEBERLIN, Barbara , STOWASSER, Frank , WIRTH, Wolfgang , BAUMBERGER, Anton , ABEL, Stephan , KAERGER, Sebastian , KIECKBUSCH, Thomas
CPC分类号： A61K9/1617 , A61K9/0075 , A61K9/145 , A61K9/1688 , A61K31/40 , A61K45/06 , A61K47/12 , A61K2300/00
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10.发明公开PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY OR OBSTRUCTIVE AIRWAY DISEASES 审中-公开用于治疗炎性或LUFTWEGVERSCHLUSSERKRANKUNGEN药物组合物
公开(公告)号：EP2059249A2
公开(公告)日：2009-05-20
申请号：EP07802989.9
申请日：2007-08-29
申请人： NOVARTIS AG
IPC分类号： A61K31/58 , A61K31/40 , A61K31/167 , A61K31/137 , A61P11/00 , A61P11/06 , A61P43/00
CPC分类号： A61K31/40 , A61K31/137 , A61K31/167 , A61K31/58 , A61K2300/00
摘要： Medicaments comprising (A) an antimuscarinic agent, (B) a beta-2 adrenoreceptor agonist and (C) a corticosteroid for the treatment of inflammatory or obstructive airways diseases.
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