公开(公告)号：EP1781699A1

公开(公告)日：2007-05-09

申请号：EP05776112.4

申请日：2005-08-16

申请人： NOVO NORDISK A/S

发明人： CONDE-FRIEBOES, Kilian, Waldemar ,  URSØ, Birgitte ,  IVERSEN, Lars, Fogh

IPC分类号： C07K14/705 ,  C07K14/715 ,  C07K16/28 ,  C07D251/12

CPC分类号： C07K14/7151

摘要： Described are compounds useful for trimerising chemical entities, methods of trimerising chemical entities, and trimerised entities. In one aspect, the entities are peptides.

公开(公告)号：EP1572669A2

公开(公告)日：2005-09-14

申请号：EP03773584.2

申请日：2003-11-20

申请人： NOVO NORDISK A/S ,  Boehringer Ingelheim International GmbH

发明人： CONDE-FRIEBOES, Kilian, Waldemar ,  ANKERSEN, Michael ,  SENSFUSS, Ulrich ,  WULFF, Birgitte, Schjellerup ,  THOGERSEN, Henning ,  LUSTENBERGER, Philipp ,  RUDOLF, Klaus ,  KRIST, Bernd ,  MÜLLER, Stephan ,  STENKAMP, Dirk ,  SCHINDLER, Marcus ,  WIELAND, Heike ,  ARNDT, Kirsten

IPC分类号： C07D241/08 ,  C07D241/06 ,  A61K31/495 ,  A61P15/10

CPC分类号： C07D401/06 ,  C07D241/08 ,  C07D401/12 ,  C07D401/14 ,  C07D403/10 ,  C07D403/12 ,  C07D403/14 ,  C07D413/14

摘要： The present invention relates to novel compounds of the general formula (I) as well as any optical or geometric isomer or tautomer form thereof, or a pharmaceutically acceptable salt thereof, as agonists of melanocortin receptors, such as agonists of the MC4 receptor. The compounds may for instance be used in the treatment of obesity.

公开(公告)号：EP2667899A1

公开(公告)日：2013-12-04

申请号：EP12708721.1

申请日：2012-01-24

申请人： Novo Nordisk A/S

发明人： KODRA, János, Tibor ,  CONDE-FRIEBOES, Kilian, Waldemar ,  PAULSSON, Johan, Fredrik ,  RAUN, Kirsten

IPC分类号： A61K47/48 ,  A61P3/04

CPC分类号： C07K14/5759 ,  A61K38/22 ,  A61K38/2264 ,  A61K47/48038 ,  A61K47/48061 ,  A61K47/542 ,  A61K47/545

摘要： The invention relates to Leptin derivatives, compositions and therapeutic use there-of.

公开(公告)号：EP1670815A2

公开(公告)日：2006-06-21

申请号：EP04762877.1

申请日：2004-09-29

申请人： NOVO NORDISK A/S

发明人： CONDE-FRIEBOES, Kilian, Waldemar ,  SENSFUSS, Ulrich ,  MADSEN, Kjeld ,  JOHANSEN, Nils, Langeland ,  CHRISTENSEN, Leif ,  HANSEN, Thomas, Kruse ,  WULFF, Birgitte Schjellerup

IPC分类号： C07K7/00

CPC分类号： C07K14/68 ,  A61K38/00

摘要： Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.

摘要翻译： 提供了包含7-12个氨基酸残基的式X1-X2-X3-X4-X5-X6-X7-R1的小环肽。 所述肽是MC4受体激动剂，因此可用于治疗肥胖症和相关疾病。