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    A PRE-FILLED DISPOSABLE INJECTION DEVICE
    2.
    发明公开
    A PRE-FILLED DISPOSABLE INJECTION DEVICE 有权
    VORGEFÜLLTEEINWEGINJEKTIONSVORRICHTUNG

    公开(公告)号：EP2911724A1

    公开(公告)日：2015-09-02

    申请号：EP13779859.1

    申请日：2013-10-22

    申请人： Novo Nordisk A/S

    发明人： BENGTSSON, Henrik ,  STEFANSEN, Mads Schenstrøm ,  EILERTSEN, Lars ,  GRÅSKOV, Henning ,  MOSER, Claus ,  BJARNSHOLT, Thomas

    IPC分类号： A61M5/32

    CPC分类号： A61M5/3257 ,  A61M5/001 ,  A61M5/002 ,  A61M5/288 ,  A61M5/31548 ,  A61M5/3202 ,  A61M5/326 ,  A61M5/3286 ,  A61M5/46 ,  A61M2005/3118 ,  A61M2005/3128 ,  A61M2005/3247 ,  A61M2005/3267 ,  A61M2209/10 ,  F04C2270/041

    摘要： The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) con- taining a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting but- ton (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed. The shield (30) carries a cleaner (50) which cleans at least the tip (24) of the needle cannula (20) between successive injections such that the prefilled injection device can be used without changing the needle cannula (20) during its life cycle.

    摘要翻译： 本发明涉及组合预填充的一次性注射装置和针插管。 预充式一次性注射装置（1）由包含不可更换的药筒（10）的壳体（2）制成，用于储存足以进行多次注射的液体药物。 预填充注射装置（1）的近端携带剂量设定按钮（3），并且远端携带具有内腔（21）的针插管（20），通过该管腔排出可设定剂量。 针管（20）的远端（23）被可伸缩的针头护罩（30）覆盖，该护罩（30）可以在覆盖针插管（20）的尖端（24）的第一位置和 第二缩回位置允许执行注射。 护罩（30）携带清洁器（50），其在连续的注射之间至少清洁针套管（20）的尖端（24），使得预填充注射装置可以在其寿命期间不改变针插管（20）而被使用 周期。

    A NEEDLE DEVICE
    4.
    发明公开
    A NEEDLE DEVICE 审中-公开
    针装置

    公开(公告)号：EP2934625A1

    公开(公告)日：2015-10-28

    申请号：EP13805413.5

    申请日：2013-12-16

    申请人： Novo Nordisk A/S

    发明人： STEFANSEN, Mads Schenstrøm ,  BENGTSSON, Henrik

    IPC分类号： A61M5/14 ,  A61M5/28 ,  A61M5/24

    CPC分类号： A61M5/322 ,  A61M5/1408 ,  A61M5/1409 ,  A61M5/2455 ,  A61M5/2466 ,  A61M5/285 ,  A61M5/288 ,  A61M5/3293 ,  A61M5/3295 ,  A61M5/343 ,  A61M2005/3206 ,  A61M2202/0007

    摘要： The invention relates to a needle device which is made from a housing (1, 2, 3) having a distal wall (4) with a front (5). The housing further holds a compartment (21, 22) containing a liquid drug to be expelled. A needle cannula (10) for expelling the liquid drug having a distal end (1 1 ) and a proximal end (12) is also present, the needle cannula (10) being axially movable from a first position to a second position; The first position being a position in which the distal end (1 1 ) of the needle cannula (10) is retracted proximally behind the front (5) of the distal wall (4) of the housing (1, 2, 3), and wherein the proximal end (12) of the needle cannula (10) is located outside the first compartment (21, 22), and the second position being a position in which the distal end (1 1 ) of the needle cannula (10) is extended distally to the front (5) of the distal wall (4) of the housing (1, 2, 3), and wherein the proximal (12) end is located inside the compartment (21, 22).

    A METHOD OF MANUFACTURING ONE OF A RANGE OF AUTOINJECTORS
    5.
    发明公开
    A METHOD OF MANUFACTURING ONE OF A RANGE OF AUTOINJECTORS 审中-公开
    制造一系列自动注射器的方法

    公开(公告)号：EP3218030A1

    公开(公告)日：2017-09-20

    申请号：EP15793849.9

    申请日：2015-11-12

    申请人： Novo Nordisk A/S

    发明人： STEFANSEN, Mads Schenstrøm ,  HANSEN, Søren Kjellerup ,  BENDIX, Klaus

    IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/32 ,  A61M5/315 ,  A61M5/50

    摘要： A method of manufacturing one of a range of autoinjectors having cartridges (600, 600′, 600″) with different preset fill volumes, the method comprising the steps of: a) providing a front body assembly (100b, 100c, 100c′, 100c″), b) providing a cartridge (600, 600′, 600″) of given fill volume, c) providing a rear body assembly (100a) comprising a spring-driven drive ram assembly (310, 320) configured to drive the piston of a held cartridge (600, 600′, 600″), d) providing a ram spacer member (400, 400′, 400″), the ram spacer member defining a spacing geometry of length dimension (X1′, X1″, X1′″, XS′, XS″, XS′″, XR′, XR″, XR′″) selected according to the fill volume of the cartridge (600, 600′, 600″), and e) assembling a front body assembly (100b, 100c, 100c′, 100c″), the cartridge (600, 600′, 600″), the ram spacer member (400, 400′, 400″) and the rear body assembly (100a) so that the ram spacer member (400, 400′, 400″) is arranged axially between the drive ram assembly (310, 320) of the rear body assembly (100a) and the piston of a held cartridge (600, 600′, 600″).

    摘要翻译： 一种制造具有不同预设填充体积的盒（600,600'，600“）的一系列自动注射器中的一个的方法，所述方法包括以下步骤：a）提供前体组件（100b，100c，100c'，100c “），b）提供给定填充体积的药筒（600,600'，600”），c）提供包括弹簧驱动推杆组件（310,320）的后体组件（100a），所述弹簧驱动推杆组件 （600,600'，600“），d）提供冲头隔离构件（400,400'，400”），冲头隔离构件限定长度尺寸（X1'，X1“，X1” （600,600'，600“）的填充体积选择，并且e）将前体组件（例如，X'，XS'，XS'，XS'，XR'，XR”，XR' （100b，100c，100c'，100c“），所述筒（600,600'，600”），所述冲头间隔件构件（400,400'，400“）和所述后主体组件（100a） 构件（400,400'，400“）轴向布置在所述r的驱动推杆组件（310,320）之间 耳体组件（100a）和保持盒（600,600'，600“）的活塞。

    AUTOINJECTOR HAVING NEEDLE SHIELD TRIGGERING
    6.
    发明公开
    AUTOINJECTOR HAVING NEEDLE SHIELD TRIGGERING 审中-公开
    AUTOINJEKTOR MITNADELABSCHIRMUNGSAUSLÖSUNG

    公开(公告)号：EP3125975A1

    公开(公告)日：2017-02-08

    申请号：EP15741942.5

    申请日：2015-04-07

    申请人： Novo Nordisk A/S

    发明人： HANSEN, Søren Kjellerup ,  STEFANSEN, Mads Schenstrøm ,  MELANDER, Matias ,  KJELDSEN, Bastian Gaardsvig

    IPC分类号： A61M5/32 ,  A61M5/315 ,  A61M5/20 ,  A61M5/24

    CPC分类号： A61M5/31501 ,  A61M5/20 ,  A61M5/24 ,  A61M5/31585 ,  A61M5/3234 ,  A61M5/3243 ,  A61M2005/2013 ,  A61M2005/2433 ,  A61M2005/247 ,  A61M2005/3247

    摘要： An autoinjector (100) for expelling a single dose of drug from a held cartridge (600) comprising a piston (630), the autoinjector comprising: a) a base (200, 220), b) a needle (500) that is fixedly mounted relative to the base (200, 220), c) a plunger (310, 320, 400) adapted for cooperation with the piston (630), d) an actuating spring (330) arranged to act on the plunger (310, 320, 400) to drive the piston (630) distally, and e) a needle shield (350, 380) axially movable relative to the base (200, 220) between an extended position and a collapsed position. In an initial state, a thread (325) of the plunger (310, 320, 400) engages a base thread (205) to maintain the plunger in an initial axial position. The autoinjector defines a lock (320, 328, 380, 388) that is released when the needle shield (350, 380) is moved from the extended position to the collapsed position. The lock (320, 328, 380, 388) releases to enable relative rotation between plunger thread (325) and base thread (205) causing release of the plunger (310, 320, 400) from the initial axial position and expelling the dose of the drug.

    摘要翻译： 一种用于从包括活塞（630）的保持的盒（600）排出单剂量药物的自动注射器（100），所述自动注射器包括：a）基座（200,220），b）固定地 相对于基座（200,220）安装，c）适于与活塞（630）配合的柱塞（310,320,400），d）致动弹簧（330），其被布置成作用在柱塞（310,320 ，400）以向远侧驱动所述活塞（630），以及e）可在延伸位置和收缩位置之间相对于所述基座（200,220）可轴向移动的针护罩（350,380）。 在初始状态下，柱塞（310,320,400）的螺纹（325）接合基线（205），以将柱塞保持在初始轴向位置。 自动注射器限定当针护罩（350,380）从延伸位置移动到折叠位置时释放的锁（320,328,380,388）。 锁定件（320,328,380,388）释放以使得柱塞螺纹（325）和基部螺纹（205）之间的相对旋转能够使柱塞（310,320,400）从初始轴向位置释放并排出 毒品。

    STATE CHANGING APPLIANCE FOR A DRUG DELIVERY DEVICE
    7.
    发明公开
    STATE CHANGING APPLIANCE FOR A DRUG DELIVERY DEVICE 审中-公开
    状态改变设备中，用于主动释放装置

    公开(公告)号：EP2934631A1

    公开(公告)日：2015-10-28

    申请号：EP13814144.5

    申请日：2013-12-20

    申请人： Novo Nordisk A/S

    发明人： STEFANSEN, Mads Schenstrøm

    IPC分类号： A61M5/315

    CPC分类号： A61M5/31525 ,  A61M5/31536 ,  A61M5/31575 ,  A61M2005/3154 ,  F04C2270/0421

    摘要： A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.