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公开(公告)号:EP2665750A1
公开(公告)日:2013-11-27
申请号:EP12708706.2
申请日:2012-01-17
申请人: Novo Nordisk A/S
发明人: SVENSSON, Lars Anders , ANDERSEN, Mette Dahl , BREINHOLT, Jens , WIBERG, Charlotte , KROGH, Berit Olsen , LUNDSGAARD, Dorthe , RASMUSSEN, Hanne Benedicte
CPC分类号: C07K16/244 , C07K14/54 , C07K2299/00 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to IL-21 ligands binding to a discontinuous epitope on the surface of the IL-21 molecule as well as use thereof.
摘要翻译: 本发明涉及结合IL-21分子表面上的不连续表位的IL-21配体及其用途。
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公开(公告)号:EP2279207A2
公开(公告)日:2011-02-02
申请号:EP09742079.8
申请日:2009-05-06
申请人: Novo Nordisk A/S
发明人: SVENSSON, Lars Anders , PADKJÆR, Søren , FRIEDRICHSEN, Birgitte , OLSEN KROGH, Berit , LUND PEDERSEN, Inger , FLECKNER, Jan
CPC分类号: C07K16/249 , C07K16/464 , C07K2317/34
摘要: The present invention provides humanized anti-human IFN-α monoclonal antibodies useful for therapeutic applications in humans. Preferred antibodies are humanized versions of murine antibodies ACO-1 and ACO-2, as well as variants thereof.
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