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公开(公告)号:EP2681237A1
公开(公告)日:2014-01-08
申请号:EP12707996.0
申请日:2012-03-01
申请人: Novo Nordisk A/S
发明人: ANDERSEN, Mette Dahl , NOERDBY, Peder Lisby , KJAERGAARD, Kristian , GRELL, Susanne Nedergaard , GRUHLER, Albrecht , BUCHARDT, Jens , ANDERSEN, Henrik Sune , PADKJAER, Soeren , KASTRUP, Jesper , HAAKANSSON, Katarina , HORNUM, Lars , FRIEDRICHSEN, Birgitte , BAUNSGAARD, Dorrit
IPC分类号: C07K14/705 , C07K16/28 , A61K39/395 , A61P37/00
CPC分类号: A61K47/6803 , A61K47/545 , A61K2039/505 , C07K14/70578 , C07K16/2863 , C07K16/2878 , C07K2317/24 , C07K2317/30 , C07K2317/34 , C07K2317/55 , C07K2317/73 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/30
摘要: The present disclosure relates to treatment of inflammatory diseases. In particular, the present disclosure relates to antagonistic DR3 ligands useful for treating inflammatory diseases.
摘要翻译: 本公开涉及炎性疾病的治疗。 特别地,本发明涉及可用于治疗炎性疾病的拮抗性DR3配体。
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公开(公告)号:EP2279207A2
公开(公告)日:2011-02-02
申请号:EP09742079.8
申请日:2009-05-06
申请人: Novo Nordisk A/S
发明人: SVENSSON, Lars Anders , PADKJÆR, Søren , FRIEDRICHSEN, Birgitte , OLSEN KROGH, Berit , LUND PEDERSEN, Inger , FLECKNER, Jan
CPC分类号: C07K16/249 , C07K16/464 , C07K2317/34
摘要: The present invention provides humanized anti-human IFN-α monoclonal antibodies useful for therapeutic applications in humans. Preferred antibodies are humanized versions of murine antibodies ACO-1 and ACO-2, as well as variants thereof.
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