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公开(公告)号:EP3307768A1
公开(公告)日:2018-04-18
申请号:EP16734567.7
申请日:2016-06-13
申请人: Novo Nordisk A/S
IPC分类号: C07K14/575 , A61K38/22 , A61K47/48 , A61P3/04
CPC分类号: C07K14/47 , A61K38/00 , A61K47/542 , C07K14/575
摘要: The invention relates to PYY compounds with the amino acid modifications 7Lys, 30Trp, and 31Leu, and in addition to these, 22Ile and/or 28Tyr, and derivatives thereof. The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.