-
公开(公告)号：EP2592081B1
公开(公告)日：2017-03-08
申请号：EP11803561.7
申请日：2011-07-05
IPC分类号： C07D471/04 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/497 , A61K45/00 , A61P11/00 , A61P13/00 , A61P13/08 , A61P17/00 , A61P19/02 , A61P21/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07D471/14 , A61K45/06 , A61K31/496
CPC分类号： A61K31/4375 , A61K31/437 , A61K31/496 , A61K45/00 , A61K45/06 , C07D471/04 , C07D471/14 , A61K2300/00
摘要： An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect. The present invention provides a compound represented by the general formula (I): (wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.
-
公开(公告)号：EP3002285B1
公开(公告)日：2018-08-29
申请号：EP15190651.8
申请日：2011-07-05
IPC分类号： C07D471/04 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/497 , A61K45/00 , A61P11/00 , A61P13/00 , A61P13/08 , A61P17/00 , A61P19/02 , A61P21/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07D471/14 , A61K45/06 , A61K31/496 , A61K31/444
CPC分类号： A61K31/437 , A61K31/4375 , A61K31/496 , A61K45/00 , A61K45/06 , C07D471/04 , C07D471/14 , A61K2300/00
摘要： An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect. The present invention provides a compound represented by the general formula (I): (wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.
-
公开(公告)号：EP2687531B1
公开(公告)日：2016-07-13
申请号：EP12761051.7
申请日：2012-01-05
IPC分类号： C07D471/14 , A61K47/26 , A61K9/20 , A61K9/19 , A61K9/00
CPC分类号： C07D471/14 , A61K9/0019 , A61K9/19 , A61K9/2054 , A61K31/435 , A61K31/437 , A61K47/26 , C07D471/04 , C07D471/12
摘要： An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect. The present invention provides a compound represented by the general formula (I): (wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.
-
公开(公告)号：EP2592081A1
公开(公告)日：2013-05-15
申请号：EP11803561.7
申请日：2011-07-05
IPC分类号： C07D471/04 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/497 , A61K45/00 , A61P11/00 , A61P13/00 , A61P13/08 , A61P17/00 , A61P19/02 , A61P21/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07D471/14
CPC分类号： A61K31/4375 , A61K31/437 , A61K31/496 , A61K45/00 , A61K45/06 , C07D471/04 , C07D471/14 , A61K2300/00
摘要： An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect.
The present invention provides a compound represented by the general formula (I):
(wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.-
公开(公告)号：EP2687531A1
公开(公告)日：2014-01-22
申请号：EP12761051.7
申请日：2012-01-05
IPC分类号： C07D471/14 , A61K31/4375 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K45/00 , A61P11/00 , A61P13/02 , A61P13/08 , A61P17/00 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00
CPC分类号： C07D471/14 , A61K9/0019 , A61K9/19 , A61K9/2054 , A61K31/435 , A61K31/437 , A61K47/26 , C07D471/04 , C07D471/12
摘要： An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect.
The present invention provides a compound represented by the general formula (I):
(wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.-
公开(公告)号：EP3002285A1
公开(公告)日：2016-04-06
申请号：EP15190651.8
申请日：2011-07-05
IPC分类号： C07D471/04 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/497 , A61K45/00 , A61P11/00 , A61P13/00 , A61P13/08 , A61P17/00 , A61P19/02 , A61P21/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07D471/14 , A61K45/06 , A61K31/496 , A61K31/444
CPC分类号： A61K31/4375 , A61K31/437 , A61K31/496 , A61K45/00 , A61K45/06 , C07D471/04 , C07D471/14 , A61K2300/00
摘要： An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect.
The present invention provides a compound represented by the general formula (I):
(wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.摘要翻译： 本发明的一个目的是提供一种对现有药物具有不同靶标作用的ENPP2抑制活性的药物，作为可用于现有药物效果不佳的尿液排泄障碍患者的药物。 本发明提供了具有ENPP2抑制活性的通式（I）所示的化合物或其盐或其溶剂合物或其前药，和（式中，各基的定义如说明书中所定义） 预防或治疗尿排泄障碍和/或改善其症状，其中含有它们作为活性成分。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.028 秒)
