Process for disinfecting musculoskeletal tissue and tissues prepared thereby
    2.
    发明公开
    Process for disinfecting musculoskeletal tissue and tissues prepared thereby 失效
    一种用于骨骼肌组织的消毒,这样调节的组织过程

    公开(公告)号:EP0740940A3

    公开(公告)日:2000-10-25

    申请号:EP96108547.9

    申请日:1990-08-06

    申请人: OSTEOTECH, INC.,

    IPC分类号: A61L2/18

    摘要: A process for treating musculoskeletal tissue which comprises contacting musculoskeletal tissue with both an effective amount at least one treating agent selected from the class consisting of antibiotics and disinfectants, and an agent to increase diffusion of the treating agent into the tissue, such as a surfactant or a permeation enhancer. The disinfectant and/or antibiotic function in killing bacteria, vegetative organisms, and viruses (including HIV virus) which may be remaining in the musculoskeletal tissue. A preferred disinfectant is ethanol. Another aspect of the invention is directed to the treatment of musculoskeletal tissue by contacting the musculoskeletal tissue with an effective viricidal amount of a surfactant.

    Aseptic processing of allograft bone and tissue
    6.
    发明公开
    Aseptic processing of allograft bone and tissue 失效
    Aseptische Behandlung von Knochen- und Gewebeallotransplantaten。

    公开(公告)号:EP0424159A2

    公开(公告)日:1991-04-24

    申请号:EP90311464.3

    申请日:1990-10-18

    申请人: OSTEOTECH, INC.,

    IPC分类号: A61L2/00 A61L27/00 A61L2/08

    摘要: The present invention comprises a method for processing allograft bone or tissue, said method comprising the steps of:

    (i) subjecting allograft bone or tissue to sterilization, said sterilization sufficient to kill microorganisms but insufficient to cause substantial physical, chemical or biological deterioration of the allograft bone or tissue; and
    (ii) aseptically processing the sterilized allograft bone or tissue resulting from step (i).

    摘要翻译: 本发明包括一种处理同种异体移植骨或组织的方法,所述方法包括以下步骤:(i)使同种异体移植骨或组织进行灭菌,所述灭菌足以杀死微生物,但不足以引起大量物理,化学或生物降解 同种异体移植骨或组织; 和(ii)无菌处理由步骤(i)得到的消毒的同种异体移植骨或组织。 Ø

    Process for disinfecting bone tissue
    7.
    发明授权
    Process for disinfecting bone tissue 失效
    一种用于骨组织在消毒过程中

    公开(公告)号:EP0740940B1

    公开(公告)日:2004-06-16

    申请号:EP96108547.9

    申请日:1990-08-06

    申请人: OSTEOTECH, INC.,

    IPC分类号: A61L2/18

    摘要: A process for treating musculoskeletal tissue which comprises contacting musculoskeletal tissue with both an effective amount at least one treating agent selected from the class consisting of antibiotics and disinfectants, and an agent to increase diffusion of the treating agent into the tissue, such as a surfactant or a permeation enhancer. The disinfectant and/or antibiotic function in killing bacteria, vegetative organisms, and viruses (including HIV virus) which may be remaining in the musculoskeletal tissue. A preferred disinfectant is ethanol. Another aspect of the invention is directed to the treatment of musculoskeletal tissue by contacting the musculoskeletal tissue with an effective viricidal amount of a surfactant.

    Process for disinfecting musculoskeletal tissue and tissues prepared thereby
    8.
    发明公开
    Process for disinfecting musculoskeletal tissue and tissues prepared thereby 失效
    Verfahren zur Desinfektion von Knochengeweben

    公开(公告)号:EP0740940A2

    公开(公告)日:1996-11-06

    申请号:EP96108547.9

    申请日:1990-08-06

    申请人: OSTEOTECH, INC.,

    IPC分类号: A61L2/18

    摘要: A process for treating musculoskeletal tissue which comprises contacting musculoskeletal tissue with both an effective amount at least one treating agent selected from the class consisting of antibiotics and disinfectants, and an agent to increase diffusion of the treating agent into the tissue, such as a surfactant or a permeation enhancer. The disinfectant and/or antibiotic function in killing bacteria, vegetative organisms, and viruses (including HIV virus) which may be remaining in the musculoskeletal tissue. A preferred disinfectant is ethanol. Another aspect of the invention is directed to the treatment of musculoskeletal tissue by contacting the musculoskeletal tissue with an effective viricidal amount of a surfactant.

    摘要翻译: 一种治疗肌肉骨骼组织的方法,其包括将肌肉骨骼组织与有效量的至少一种选自抗生素和消毒剂的治疗剂接触,以及增加治疗剂扩散到组织例如表面活性剂或 渗透增强剂。 杀死细菌,营养生物和可能存在于肌肉骨骼组织中的病毒(包括HIV病毒)的消毒剂和/或抗生素功能。 优选的消毒剂是乙醇。 本发明的另一方面涉及通过使肌肉骨骼组织与有效的杀病毒剂量的表面活性剂接触来治疗肌肉骨骼组织。