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1.发明公开COMPOSITIONS USEFUL IN THE TREATMENT OF DISEASES OF CONNECTIVE TISSUES COMPRISING A FERROUS ION AND AN ASCORBATE 有权用于治疗结缔组织的组合物，铁（II）离子和抗坏血酸CONTAIN
公开(公告)号：EP1276485A2
公开(公告)日：2003-01-22
申请号：EP01927527.0
申请日：2001-04-25
CPC分类号： A61K31/375 , A61K31/7008 , A61K33/26 , A61K31/7004 , A61K2300/00
摘要： Compositions comprising ferrous ion and an ascorbate have a synergistic effect on cartilage development. Therapeutic compositions comprising ferrous ion and an ascorbate are therefore useful in the treatment of osteoarthritis. The addition of a glucosamine, such as glucosamine hydrochloride, to the composition has a further enhanced effect on cartilage production. Therapeutic compositions comprising ferrous ion, an ascorbate and a glucosamine derivative are even more useful in the treatment of osteoarthritis.
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2.发明授权COMPOSITIONS USEFUL IN THE TREATMENT OF DISEASES OF CONNECTIVE TISSUES COMPRISING A FERROUS ION AND AN ASCORBATE 有权用于治疗结缔组织的组合物，铁（II）离子和抗坏血酸CONTAIN
公开(公告)号：EP1276485B1
公开(公告)日：2006-08-02
申请号：EP01927527.0
申请日：2001-04-25
CPC分类号： A61K31/375 , A61K31/7008 , A61K33/26 , A61K31/7004 , A61K2300/00
摘要： Compositions comprising ferrous ion and an ascorbate have a synergistic effect on cartilage development. Therapeutic compositions comprising ferrous ion and an ascorbate are therefore useful in the treatment of osteoarthritis. The addition of a glucosamine, such as glucosamine hydrochloride, to the composition has a further enhanced effect on cartilage production. Therapeutic compositions comprising ferrous ion, an ascorbate and a glucosamine derivative are even more useful in the treatment of osteoarthritis.
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