专利检索 ap:("Okinawa Institute of Science AND Technology School Corporation") AND inv:"CUI, Hai-Lei" 第 1 页

1.

发明授权
NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME 有权

公开(公告)号：EP2888268B1

公开(公告)日：2018-08-22

申请号：EP13846040.7

申请日：2013-10-04

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CUI, Hai-Lei , TANAKA, Fujie

IPC分类号： C07D491/107 , A61K31/407 , A61P35/00

CPC分类号： C07D491/107

摘要： Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.

2.

发明公开
NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：新型SPIROOXINDOLDERIVAT THEREOF及其制备方法

公开(公告)号：EP2888268A1

公开(公告)日：2015-07-01

申请号：EP13846040.7

申请日：2013-10-04

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CUI, Hai-Lei , TANAKA, Fujie

IPC分类号： C07D491/107 , A61K31/407 , A61P35/00

CPC分类号： C07D491/107

摘要： Disclosed is a compound of formula I: wherein Rｿ1?, Rｿ2?, Rｿ3?, Rｿ4?, Rｿ5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.