专利检索 ap:("Okinawa Institute of Science AND Technology School Corporation") AND inv:"TANAKA, Fujie" 第 1 页

1.

发明授权
4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME 有权

公开(公告)号：EP3191451B1

公开(公告)日：2019-06-05

申请号：EP15840917.7

申请日：2015-09-09

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CHOUTHAIWALE, Pandurang Vilasrao , TANAKA, Fujie

IPC分类号： C07D213/79 , A61K31/4418 , A61P9/10 , A61P11/00 , A61P17/06 , A61P29/00 , A61P35/00

2.

发明授权
NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME 有权

公开(公告)号：EP2888268B1

公开(公告)日：2018-08-22

申请号：EP13846040.7

申请日：2013-10-04

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CUI, Hai-Lei , TANAKA, Fujie

IPC分类号： C07D491/107 , A61K31/407 , A61P35/00

CPC分类号： C07D491/107

摘要： Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.

3.

发明公开
NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：新型SPIROOXINDOLDERIVAT THEREOF及其制备方法

公开(公告)号：EP2888268A1

公开(公告)日：2015-07-01

申请号：EP13846040.7

申请日：2013-10-04

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CUI, Hai-Lei , TANAKA, Fujie

IPC分类号： C07D491/107 , A61K31/407 , A61P35/00

CPC分类号： C07D491/107

摘要： Disclosed is a compound of formula I: wherein Rｿ1?, Rｿ2?, Rｿ3?, Rｿ4?, Rｿ5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.

4.

发明公开
4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME 审中-公开
标题翻译： 4-取代的吡啶-2,6-二羧酸衍生物及其制备方法

公开(公告)号：EP3191451A1

公开(公告)日：2017-07-19

申请号：EP15840917.7

申请日：2015-09-09

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CHOUTHAIWALE, Pandurang Vilasrao , TANAKA, Fujie

IPC分类号： C07D213/79 , A61K31/4418 , A61P9/10 , A61P11/00 , A61P17/06 , A61P29/00 , A61P35/00

CPC分类号： C07D213/79 , A61P35/00 , C07D213/803 , C07D405/04

摘要： The present invention relates to novel 4-substituted pyridine-2,6-dicarboxylic acid derivatives, compounds of formula I, wherein R1 and R2 are defined herein. The compounds of formula I are useful for making pharmaceutical compositions to treat proliferative diseases. The present invention also relates to concise methods for preparing compounds of formula I that may be performed under mild reaction conditions.

摘要翻译： 本发明涉及新的4-取代的吡啶-2,6-二羧酸衍生物，式I化合物，其中R1和R2在本文中定义。式I化合物可用于制备治疗增殖性疾病的药物组合物。本发明还涉及制备可在温和反应条件下进行的式I化合物的简明方法。

5.

发明授权
PROCESS FOR PRODUCING DIHYDRO-2H-PYRAN DERIVATIVES 有权
标题翻译：用于生产二氢-2H-吡喃衍生物

公开(公告)号：EP2885282B1

公开(公告)日：2017-03-15

申请号：EP13845790.8

申请日：2013-10-10

申请人： Okinawa Institute of Science and Technology School Corporation

发明人： CHOUTHAIWALE, Pandurang V. , TANAKA, Fujie

IPC分类号： C07D309/30 , A61K31/215 , A61K31/351 , A61K31/357 , A61K31/498 , A61K31/551 , A61P35/00 , C07C201/14 , C07C205/55 , C07D241/44 , C07D243/02 , C07D307/54 , C07D309/28 , C07D317/30 , C07D407/04

CPC分类号： C07D309/28 , C07C201/14 , C07C205/55 , C07C2601/14 , C07D241/44 , C07D243/02 , C07D307/54 , C07D309/30 , C07D317/30 , C07D407/04