专利检索 ap:("Ontario Institute for Cancer Research (OICR)" OR "The Governing Council of the University of Toronto" OR "Sinai Health System") AND inv:"ISAAC, Methvin" 第 1 页

1.

发明公开
ISOINDOLINONE AMINOPYRIMIDINE COMPOUNDS AS INHIBITORS OF NUAK KINASES, COMPOSITIONS AND USES THEREOF 审中-公开

公开(公告)号：EP4277902A1

公开(公告)日：2023-11-22

申请号：EP22736481.7

申请日：2022-01-07

申请人： Ontario Institute for Cancer Research (OICR) , The Governing Council of the University of Toronto , Sinai Health System

发明人： AL-AWAR, Rima , ATTISANO, Liliana , ISAAC, Methvin , LIU, Yong , SMIL, David , UEHLING, David , WRANA, Jeff

IPC分类号： C07D401/14 , A61K31/55 , A61K31/506 , A61K31/551 , A61P19/04 , A61P35/00 , C07D403/12 , C07D403/14 , C07D471/10 , C07D487/04 , C07D487/08

2.

发明公开
THIENYL AND CYCLOALKYL AMINOPYRIMIDINE COMPOUNDS AS INHIBITORS OF NUAK KINASES, COMPOSITIONS AND USES THEREOF 审中-公开

公开(公告)号：EP4274829A1

公开(公告)日：2023-11-15

申请号：EP22736479.1

申请日：2022-01-07

申请人： Ontario Institute for Cancer Research (OICR) , The Governing Council of the University of Toronto , Sinai Health System

发明人： AL-AWAR, Rima , ATTISANO, Liliana , ISAAC, Methvin , LIU, Yong , SMIL, David , UEHLING, David , WRANA, Jeff

IPC分类号： C07D409/14 , A61K31/506 , A61K31/551 , A61K31/5383 , A61P35/00 , C07D239/48 , C07D241/36 , C07D409/12 , C07D451/02 , C07D471/10 , C07D487/04 , C07D498/04

3.

发明公开
HALO-SUBSTITUTED AMINO AZA-HETEROARYL COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) 审中-公开

公开(公告)号：EP4330246A1

公开(公告)日：2024-03-06

申请号：EP22794165.5

申请日：2022-05-02

申请人： Ontario Institute for Cancer Research (OICR)

发明人： CHAU, Anh , ISAAC, Methvin , JOSEPH, Babu , LAUFER, Radek , PODA, Gennady , PRAKESCH, Michael , UEHLING, David , WATSON, Iain , WILSON, Brian , XIN, Tao

IPC分类号： C07D401/04 , A61K31/497 , A61K31/502 , A61K31/517 , A61K31/5377 , A61K31/5386 , A61P35/00 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/10 , C07D498/10

4.

发明公开
NOVEL QUINOLONE COMPOUNDS AS INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND/OR AS BCL6 DEGRADERS 审中-公开

公开(公告)号：EP3728232A1

公开(公告)日：2020-10-28

申请号：EP18890785.1

申请日：2018-12-20

申请人： Ontario Institute for Cancer Research (OICR)

发明人： ISAAC, Methvin , CHAU, Anh My

IPC分类号： C07D401/14 , A61K31/506 , A61P35/00 , A61P35/02

5.

发明公开
TRICYCLIC INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF 审中-公开

公开(公告)号：EP3728267A1

公开(公告)日：2020-10-28

申请号：EP18890670.5

申请日：2018-12-21

申请人： Ontario Institute for Cancer Research (OICR)

发明人： AL-AWAR, Rima , ISAAC, Methvin , CHAU, Anh My , MAMAI, Ahmed , WATSON, Iain , PODA, Gennady , SUBRAMANIAN, Pandiaraju , WILSON, Brian , UEHLING, David

IPC分类号： C07D487/14 , A61K31/519 , A61K31/5377 , A61K31/55 , A61P35/00 , A61P35/02 , C07D519/00

6.

发明公开
NOVEL DEUTERATED COMPOUNDS AS INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND/OR AS BCL6 DEGRADERS 审中-公开

公开(公告)号：EP3728231A1

公开(公告)日：2020-10-28

申请号：EP18890560.8

申请日：2018-12-21

申请人： Ontario Institute for Cancer Research (OICR)

发明人： ISAAC, Methvin , CHAU, Anh My , MAMAI, Ahmed

IPC分类号： C07D401/14 , A61K31/506 , A61P35/00

7.

发明公开
SUBSTITUTED AMINO AZA-HETEROARYL COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) 审中-公开

公开(公告)号：EP4330252A1

公开(公告)日：2024-03-06

申请号：EP22794166.3

申请日：2022-05-02

申请人： Ontario Institute for Cancer Research (OICR)

发明人： AL-AWAR, Rima , ISAAC, Methvin , JOSEPH, Babu , LAUFER, Radek , POSTERNAK, Ganna , PRAKESCH, Michael , UEHLING, David , WATSON, Iain , WILSON, Brian , ZEPEDA-VELAZQUEZ, Carlos Armando , CHAU, Anh , XIN, Tao

IPC分类号： C07D403/04 , A61K31/53 , A61K31/497 , A61K31/5377 , A61P35/00 , C07D403/14 , C07D405/14 , C07D413/14