公开(公告)号：EP1942932A2

公开(公告)日：2008-07-16

申请号：EP06851676.4

申请日：2006-08-07

申请人： Oregon Health and Science University

发明人： SLIFKA, Mark, K. ,  CARTER, Shirley, W. ,  HAMMARLUND, Erika ,  YOSHIHARA, Paul

IPC分类号： A61K39/00 ,  A61K39/285

CPC分类号： A61K39/285 ,  A61K33/40 ,  A61K39/00 ,  A61K39/12 ,  A61K39/275 ,  A61K2039/521 ,  A61K2039/5252 ,  A61K2039/55572 ,  C12N2710/24034 ,  C12N2710/24063 ,  C12N2710/24134 ,  C12N2710/24163 ,  C12N2760/10063 ,  C12N2770/24163

摘要： The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are suitable for the preparation of vaccines for a wide variety of pathogens, including viruses, bacteria and parasites. The disclosure also provides vaccine compositions (medicaments) containing a pathogen inactivated by exposure to hydrogen peroxide. Methods for eliciting an immune response in a subject by administering vaccine compositions containing a hydrogen peroxide inactivated pathogen are also provided.